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Publication Results (1037)

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  • Direct healthcare costs of acute myocardial infarction in Canada’s elderly across the continuum of care

    Cohen D, Manuel DG, Tugwell P, Sanmartin C, Ramsay T. J Econ Ageing. 2014; 3:44-9.

  • Seasonal variation in rates of emergency room visits and acute admissions following recommended infant vaccinations in Ontario, Canada: a self-controlled case series analysis

    Hawken S, Potter BK, Benchimol EI, Little J, Ducharme R, Wilson K. Vaccine. 2014; 32(52):7148-53. Epub 2014 Nov 1.

  • The effect of multidisciplinary heart failure clinic characteristics on 1-year postdischarge health care costs: a population-based study

    Wijeysundera HC, Austin PC, Wang X, Bennell MC, Abrahamyan L, Ko DT, Tu JV, Krahn M. Med Care. 2014; 52(3):272-9. Epub 2014 Feb 24.

  • Incidence and prevalence of MS in children: a population-based study in Ontario, Canada

    Marrie RA, O’Mahony J, Maxwell C, Ling V, Yeh EA, Arnold DL, Bar-Or A, Banwell B; Canadian Pediatric Demyelinating Disease Network. Neurology. 2018; 91(17):e1579-90. Epub 2018 Sep 26.

  • Validation of international algorithms to identify adults with inflammatory bowel disease in health administrative data from Ontario, Canada

    Benchimol EI, Guttmann A, Mack DR, Nguyen GC, Marshall JK, Gregor JC, Wong J, Forster AJ, Manuel DG. J Clin Epidemiol. 2014; 67(8):887-96. Epub 2014 Apr 26.

  • February 2019

    • Social licence and the general public’s attitudes toward research based on linked administrative health data, a qualitative study
    • Do doctors who order more routine medical tests diagnose more cancers? A population-based study from Ontario, Canada
    • Injection of opioids linked to increase in bacterial heart infections
    • Cause-specific mortality among HIV-infected people in Ontario, 1995–2014: a population-based retrospective cohort study
    • Association of surgical intervention for adhesive small-bowel obstruction with the risk of recurrence
    ICES in the News
    • How using your Ontario health card creates system change
    • Infertility treatment and risk of severe maternal morbidity: a propensity score-matched cohort study
    • Association of transvaginal mesh complications with the risk of new-onset depression or self-harm in women with a midurethral sling
    • Inflammatory bowel disease and new-onset psychiatric disorders in pregnancy and post-partum: a population based cohort study
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    • The risk of heart failure and other cardiovascular hospitalizations after early stage breast cancer: a matched cohort study
    • One-year survival and admission to hospital for cardiovascular events among older residents of long-term care facilities who were prescribed intensive- and moderate-dose statins
    • Healthcare utilization costs of emerging adults with mood and anxiety disorders in an early intervention treatment program compared to a matched cohort
    • Survival and health care use after feeding tube placement in children with neurologic impairment
    • Disparities in breast cancer diagnosis for immigrant women in Ontario and BC: results from the CanIMPACT study
  • Obstructive sleep apnoea is not a risk factor for incident hospitalised depression: a historical cohort study

    Kendzerska T, Gershon AS, Hawker GA, Tomlinson GA, Leung RS. Eur Respir J. 2017; 49(6):1601361. Epub 2017 Jun 1.

  • Concomitant pulmonologist and primary care for chronic obstructive pulmonary disease: a population study

    Gershon AS, Macdonald EM, Luo J, Austin PC, Gupta S, Sivjee K, Upshur R, Aaron SD. Fam Pract. 2017; 34(6):708-16. Epub 2017 Jul 7.
  • Addressing Gaps in the Health Care Services Used by Adults with Developmental Disabilities in Ontario

    Lin E, Balogh RS, Durbin A, Holder L, Gupta N, Volpe T, Isaacs BJ, Weiss JA, Lunsky Y. February 2019.

  • A population-based study of the resource utilization and costs of managing resectable non-small cell lung cancer

    Mahar AL, Coburn NG, Johnson AP. Lung Cancer. 2014; 86(2):281-7. Epub 2014 Sep 20.

  • Importance of completing hybrid cardiac rehabilitation for long-term outcomes: a real-world evaluation

    Suskin NG, Shariff SZ, Garg AX, Reid J, Unsworth K, Prior PL, Alter D. J Clin Med. 2019; 8(3):E290. Epub 2019 Feb 28.

  • Pregabalin and heart failure: a population-based study

    Ho JM, Macdonald EM, Luo J, Gomes T, Antoniou T, Mamdani MM, Juurlink DN. Pharmacoepidemiol Drug Saf. 2017; 26(9):1087-92. Epub 2017 Jun 16.

  • Varenicline and risk of self-harm: a nested case-control study

    Tadrous M, Martins D, Yao Z, Mamdani MM, Juurlink DN, Gomes T, Antoniou T. PLoS One. 2016; 11(9):e0163681.

  • Catastrophic drug coverage: utilization insights from the Ontario Trillium Drug Program

    Tadrous M, Greaves S, Martins D, Mamdani MM, Juurlink DN, Gomes T. CMAJ Open. 2018; 6(1):E132-8. Epub 2018 Mar 26.

  • New thyroxine treatment in older adults beginning lithium therapy: implications for clinical practice

    Shulman KI, Sykora K, Gill SS, Mamdani M, Anderson G, Marras C, Wodchis WP, Lee PE, Rochon P. Am J Geriatr Psychiatry. 2005; 13(4):299-304.

  • Management of neuropsychiatric symptoms in long-term care residents with Parkinson's disease: a retrospective cohort study

    Herrmann N, Marras C, Fischer HD, Wang X, Anderson GM, Rochon PA. Drugs Aging. 2013; 30(1):19-22. Epub 2012 Nov 28.

  • July 2019

    • Changing rates of self-harm and mental disorders by sex in youths presenting to Ontario emergency departments: repeated cross-sectional study
    • Same-day discharge after elective percutaneous coronary interventions in Ontario, Canada
    • Management of sleep disorders in community-dwelling older women and men at the time of diagnosis
    • The risk of cardiovascular events on cannabis’ highest day
    ICES in the News
    • Interaction between neighborhood walkability and traffic-related air pollution on hypertension and diabetes: the CANHEART cohort
    • Introduction of anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases: a population-based interrupted time series study
    • Geographic Variation in Primary Care Need, Service Use and Providers in Ontario, 2015/16
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    • Risk of hospitalization for serious adverse gastrointestinal events associated with sodium polystyrene sulfonate use in patients of advanced age
    • Primary care performance of alternatively licenced physicians in Ontario, Canada: a cross-sectional study using administrative data
    • Adherence to predefined dietary patterns and risk of developing type 2 diabetes in the Canadian adult population
    • The urine culturing cascade: variation in nursing home urine culturing and association with antibiotic use and C. difficile infection
    • A challenge to all. A primer on inter-country differences of high-need, high-cost patients
    • Suicide and self-harm in recent immigrants in Ontario, Canada: a population-based study
  • September 2019

    • Risks of preoperative anemia in women undergoing elective hysterectomy and myomectomy
    • Sex-specific differences in end-of-life burdensome interventions and antibiotic therapy in nursing home residents with advanced dementia
    • Chronic physical conditions and risk for perinatal mental illness: a population-based retrospective cohort study
    • Physician availability in long-term care and resident hospital transfer: a retrospective cohort study
    ICES in the News
    • Population-based secular trends in lower extremity amputation for diabetes and peripheral artery disease
    • Opioid prescribing after surgery in the United States, Canada and Sweden
    • Sex differences in long‐term survival after major cardiac surgery: a population‐based cohort study
    • Trends in the use of cardiac imaging for patients with heart failure in Canada
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    • Days spent at home in the last 6 months of life: a quality indicator of end of life care in patients with hematologic malignancies
    • Trends in use of medical imaging in US health care systems and in Ontario, Canada, 2000-2016
    • Ambient air pollution and the risk of atrial fibrillation and stroke: a population-based cohort study
    • Incidence of hospitalizations and emergency department visits for herpes zoster in immunocompromised and immunocompetent adults in Ontario, Canada, 2002-2016
    • Understanding those overdue for cancer screening by five years or more: a retrospective cohort study in Ontario, Canada
    • Impact of the 2016 policy change on the delivery of Medscheck services in Ontario: an interrupted time-series analysis
    • The impact of hospital harm on length of stay, costs of care and length of person-centred episodes of care: a retrospective cohort study
  • Assessing the performance of the generalized propensity score for estimating the effect of quantitative or continuous exposures on survival or time-to-event outcomes

    Austin PC. Stat Methods Med Res. 2019; 28(8):2348-67. Epub 2018 Jun 5. DOI: 10.1177/0962280218776690.

  • January 2020

    Impact Stories
    • Surgical duration is associated with an increased risk of periprosthetic infection following total knee arthroplasty: a population-based retrospective cohort study
    • The risk of death within five years of first hospitalization in older adults
    • Determinants of direct discharge home from critical care units: a population-based cohort analysis
    • High-cost patients and preventable spending: a population-based study
    • Prescribing of oral anticoagulants in the emergency department and subsequent long-term use by older adults with atrial fibrillation
      ICES in the News
      • Neighbourhood-level marginalization and avoidable mortality in Ontario, Canada: a population-based study
      • Association of patient, prescriber, and region with the initiation of first prescription of biologic disease-modifying antirheumatic drug among older patients with rheumatoid arthritis and identical health insurance coverage
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      • Characterising risk of homicide in a population-based cohort
      • Association between hospital teaching status and outcomes after out-of-hospital cardiac arrest
      • The direct healthcare costs attributable to West Nile virus illness in Ontario, Canada: a population-based cohort study using laboratory and health administrative data
      • Resident trainees increase surgical time: a comparison of obstetric and gynaecologic procedures in academic versus community hospitals
      • Comparative effectiveness of fluoroquinolone antibiotic use in uncomplicated acute exacerbations of COPD: a multi-cohort study
      • Changes in opioid prescribing behaviors among family physicians who participated in a weekly tele-mentoring program
      • A new record linkage for assessing infant mortality rates in Ontario, Canada
    • Closed for business? Using a mixture model to explore the supply of psychiatric care for new patients

      Rudoler D, de Oliveira C, Zaheer J, Kurdyak P. Can J Psychiatry. 2019; 64(6):568-76. Epub 2019 Feb 25. DOI: 10.1177/0706743719828963.

    • Cardiovascular consequences of obstructive sleep apnea in women: a historical cohort study

      Kendzerska T, Leung R, Atzema C, Chandy G, Meteb M, Malhotra A, Hawker G, Gershon AS. Sleep Med. 2020; 68:71-9. Epub 2019 Sep 11. DOI: 10.1016/j.sleep.2019.08.021.

    • Factors associated with diabetes care quality among patients with schizophrenia in Ontario, Canada

      Hsu JH, Calzavara A, Vigod S, Stukel TA, Kiran T, Kurdyak P. Psychiatr Serv. 2020; 71(2):188-91. Epub 2019 Nov 20.

    • March 2020

      • Ethnic variation in the conversion of prediabetes to diabetes among immigrant populations relative to Canadian-born residents: a population-based cohort study
      • Evaluation of a common prescribing cascade of calcium channel blockers and diuretics in older adults with hypertension
      • Association of tympanostomy tubes with future assistive hearing devices – a population based study
        ICES in the News
        • Early experience with medical assistance in dying in Ontario, Canada: a cohort study
        • Validation study of health administrative data algorithms to identify individuals experiencing homelessness and estimate population prevalence of homelessness in Ontario, Canada
        • Incidence of chronic obstructive pulmonary disease in people with HIV in Ontario, 1996–2015: a retrospective population-based cohort study
        • Diabetes prevalence, incidence and mortality in First Nations and other people in Ontario, 1995–2014: a population-based study using linked administrative data
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        • Effectiveness of confidential reports to physicians on their prescribing of antipsychotic medications in nursing homes
        • Estimating the net benefit of improvements in hospital performance: G-computation with hierarchical regression models
        • Publicly funded home care service use in the first 2 years after spinal cord injury in Ontario, Canada
        • Antibiotic prescribing choices and their comparative C. difficile infection risks: a longitudinal case-cohort study
        • Comparing an artificial neural network to logistic regression for predicting ED visit risk among patients with cancer: a population-based cohort study
        • The association between climate, geography and respiratory syncitial virus hospitalizations among children in Ontario, Canada: a population-based study
        • Urgent outpatient care following mental health ED visits: a population-based study
        • Comparison of payment changes and Choosing Wisely recommendations for use of low-value laboratory tests in the United States and Canada
      • April 2020

        • Geographic access to stroke care services in rural communities in Ontario, Canada
        • Association of immigrant and refugee status with risk factors for exposure to violent assault among youths and young adults in Canada
        • Physician-based availability of psychotherapy in Ontario: a population-based retrospective cohort study
          ICES in the News
          • Association between road traffic noise and incidence of diabetes mellitus and hypertension in Toronto, Canada: a population‐based cohort study
          • Increased risk of dementia among overactive bladder patients treated with an anticholinergic medication compared to a beta-3 agonist: a population-based cohort study
          • Canada and COVID-19: learning from SARS
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          • Increasing complexity of new nursing home residents in Ontario, Canada: a serial cross-sectional study
          • Intra-provincial variation in publicly funded mental health and addictions “services” use among Canadian Armed Forces families posted across Ontario
          • Benefits of high-volume medical oncology care for noncurable pancreatic adenocarcinoma: a population-based analysis
          • Assessing the impact of early identification of patients appropriate for palliative care on resource use and costs in the final month of life
          • Characterizing risk of type 2 diabetes in First Nations people living in First Nations communities in Ontario: a population-based analysis using cross-sectional survey data
          • Health system costs for cancer medications and radiation treatment in Ontario for the 4 most common cancers: a retrospective cohort study
          • Does physician compensation for declaration of involuntary status increase the likelihood of involuntary admission? A population-level cross-sectional linked administrative database study
          • Association of primary care involvement with death or hospitalizations for patients starting dialysis
        • Factors affecting the delivery of community pharmacist-led medication reviews: evidence from the MedsCheck annual service in Ontario

          Pechlivanoglou P, Abrahamyan L, MacKeigan L, Consiglio GP, Dolovich L, Li P, Cadarette SM, Rac VE, Shin J, Krahn M. BMC Health Serv Res. 2016; 16:666. Epub 2016 Nov 21.

        • Serious infections in patients with myasthenia gravis: population-based cohort study

          Kassardjian CD, Widdifield J, Paterson JM, Kopp A, Nagamuthu C, Barnett C, Tu K, Breiner A. Eur J Neurol. 2020; 27(4):702-8. Epub 2020 Jan 29. DOI:

        • Impact of Clostridium difficile colitis on 5-year health outcomes in patients with ulcerative colitis

          Murthy SK, Steinhart AH, Tinmouth J, Austin PC, Daneman N, Nguyen GC. Aliment Pharmacol Ther. 2012; 36(11-12):1032-9. Epub 2012 Oct 14.

        • June 2020

          • Mood disorders in late life: a population-based analysis of prevalence, risk factors, and consequences in community-dwelling older adults in Ontario
          • Implementation of a physician incentive program for 18-month developmental screening in Ontario, Canada
          • Interventions supporting long term adherence and decreasing cardiovascular events after myocardial infarction (ISLAND): pragmatic randomised controlled trial
          ICES in the News
          • COVID-19 Laboratory Testing in Ontario: Patterns of Testing and Characteristics of Individuals Tested, as of April 30, 2020
          • Risk of hospitalization with hemorrhage among older adults taking clarithromycin vs azithromycin and direct oral anticoagulants
          • ICES’ new three-year strategic plan now available
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          • After-hours incentives and emergency department visits: evidence from Ontario
          • Identifying drugs with disease-modifying potential in Parkinson's disease using artificial intelligence and pharmacoepidemiology
          • In-hospital patient harm across linguistic groups: a retrospective cohort study of home care recipients
          • Healthcare costs and resource utilization associated with treatment of out-of-hospital cardiac arrest
          • Cancer staging in individuals with a severe psychiatric illness: a cross-sectional study using population-based cancer registry data
          • Treatment patterns and outcomes in adolescents and young adults with Hodgkin lymphoma in pediatric versus adult centers: an IMPACT cohort study
          • The impact of different antibiotic treatment regimens on mortality in Mycobacterium avium complex pulmonary disease (MAC-PD): a population-based cohort study
          • Association between the regional variation in premature mortality and immigration in Ontario, Canada
        • Universal bilirubin screening and health care utilization

          Darling EK, Ramsay T, Sprague AE, Walker MC, Guttmann A. Pediatrics. 2014; 134(4):e1017-24.

        • Missed strokes using computed tomography imaging in patients with vertigo: population-based cohort study

          Grewal K, Austin PC, Kapral MK, Lu H, Atzema CL. Stroke. 2015; 46(1):108-13. Epub 2014 Dec 4.

        • Temporal trends in sudden cardiac death in Ontario, Canada

          Shuvy M, Qiu F, Lau G, Koh M, Dorian P, Geri G, Lin S, Ko DT. Resuscitation. 2019; 136:1-7. Epub 2019 Jan 14.

        • The cost of childhood intussusception in Ontario from 2003 to 2016: a population-based study

          Pilkington M, Khong E, Brogly SB, Winthrop A, Kolar M. J Pediatr Surg. 2020; 55(5):883-8. Epub 2020 Jan 31. DOI:

        • Identifying and characterizing psoriasis and psoriatic arthritis patients in Ontario administrative data: a population-based study from 1991 to 2015

          Eder L, Widdifield J, Rosen CF, Alhusayen R, Cheng SY, Young J, Campbell W, Bernatsky S, Gladman DD, Paterson JM, Tu K. J Rheumatol. 2020; 47(11):1644-51. Epub 2020 Feb 15. DOI:

        • The prevalence and health status of people with developmental disabilities in provincial prisons in Ontario, Canada: a retrospective cohort study

          Whittingham L, Durbin A, Lin E, Matheson FI, Volpe T, Dastoori P, Calzavara A, Lunsky Y, Kouyoumdjian F. J Appl Res Intellect Disabil. 2020; 33(6):1368-79. Epub 2020 June 11. DOI:

        • December 2020

          • Mortality among patients with frequent emergency department use for alcohol-related reasons in Ontario: a population-based cohort study
          • Association between ABO and Rh blood groups and SARS-CoV-2 infection or severe COVID-19 illness: a population-based cohort study
          • Diagnostic testing in long-term care and resident emergency department visits: a retrospective cohort study
          ICES in the News
          • COVID-19 in Ontario
          • Life expectancy and health-adjusted life expectancy in people with inflammatory bowel disease
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          • Association between neuraxial anaesthesia or general anaesthesia for lower limb revascularisation surgery in adults and clinical outcomes: population based comparative effectiveness study
          • Economic burden of epilepsy in children: a population-based matched cohort study in Canada
          • Combined associations of work and leisure time physical activity on incident diabetes risk
          • Mental health and addictions system performance in Ontario: an updated scorecard, 2009-2017
          • Higher-dose sitagliptin and the risk of congestive heart failure in older adults with CKD
          • Feminization of the rheumatology workforce: a longitudinal evaluation of patient volumes, practice sizes and physician remuneration
          • The LENT index predicts 30 day outcomes following hospitalization for heart failure
          • Sex-specific temporal trends in ambulatory heart failure incidence, mortality and hospitalisation in Ontario, Canada from 1994 to 2013: a population-based cohort study
        • January 2021

          • ICES Winter Forum
          • Testing, infection and complication rates of COVID-19 among people with a recent history of homelessness in Ontario, Canada: a retrospective cohort study
          • Impact of geography on care delivery and survival for noncurable pancreatic adenocarcinoma: a population-based analysis
          • Patient-reported symptom burden as a predictor of emergency department use and unplanned hospitalization in head and neck cancer: a longitudinal population-based study
          ICES in the News
          • A health care system besieged by COVID?
          • COVID-19 in Ontario
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          • Medication use and its impact on high-cost health care users among older adults: protocol for the population-based matched cohort HiCOSTT study
          • Quality and safety in long-term care in Ontario: the impact of language discordance
          • Over half of seniors who start oral bisphosphonate therapy are exposed for 3 or more years: novel rolling window approach and patterns of use
          • Statin exposure and risk of heart failure after anthracycline- or trastuzumab-based chemotherapy for early breast cancer: a propensity score-matched cohort study
          • Access to bariatric surgery among older patients in a publicly funded regionalized care system
          • Mental health services provision in primary care and emergency department settings: analysis of blended fee-for-service and blended capitation models in Ontario, Canada
          • Correlates of non-adherence to breast, cervical, and colorectal cancer screening among screen-eligible women: a population-based cohort study in Ontario, Canada
          • Effect of socio-demographic and health factors on the association between multimorbidity and acute care service use: population-based survey linked to health administrative data
        • Concussion in adolescence and the risk of multiple sclerosis: a retrospective cohort study

          Povolo CA, Reid JN, Shariff SZ, Welk B, Morrow SA. Mult Scler. 2021; 27(2):180-7. Epub 2020 Feb 24. DOI:

        • The effect of a constraint on the maximum number of controls matched to each treated subject on the performance of full matching on the propensity score when estimating risk differences

          Austin PC, Stuart EA. Stat Med. 2021; 40(1):101-18. Epub 2020 Oct 7. DOI:

        • Frailty and long-term outcomes following critical illness: a population-level cohort study

          Hill AD, Fowler RA, Wunsch H, Pinto R, Scales DC. J Crit Care. 2021; 62:94-100. Epub 2020 Dec 1. DOI: