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Publication Results (568)

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  • July 2019

    • Changing rates of self-harm and mental disorders by sex in youths presenting to Ontario emergency departments: repeated cross-sectional study
    • Same-day discharge after elective percutaneous coronary interventions in Ontario, Canada
    • Management of sleep disorders in community-dwelling older women and men at the time of diagnosis
    • The risk of cardiovascular events on cannabis’ highest day
    ICES in the News
    • Interaction between neighborhood walkability and traffic-related air pollution on hypertension and diabetes: the CANHEART cohort
    • Introduction of anti-TNF therapy has not yielded expected declines in hospitalisation and intestinal resection rates in inflammatory bowel diseases: a population-based interrupted time series study
    • Geographic Variation in Primary Care Need, Service Use and Providers in Ontario, 2015/16
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    • Risk of hospitalization for serious adverse gastrointestinal events associated with sodium polystyrene sulfonate use in patients of advanced age
    • Primary care performance of alternatively licenced physicians in Ontario, Canada: a cross-sectional study using administrative data
    • Adherence to predefined dietary patterns and risk of developing type 2 diabetes in the Canadian adult population
    • The urine culturing cascade: variation in nursing home urine culturing and association with antibiotic use and C. difficile infection
    • A challenge to all. A primer on inter-country differences of high-need, high-cost patients
    • Suicide and self-harm in recent immigrants in Ontario, Canada: a population-based study
  • April 2020

    • Geographic access to stroke care services in rural communities in Ontario, Canada
    • Association of immigrant and refugee status with risk factors for exposure to violent assault among youths and young adults in Canada
    • Physician-based availability of psychotherapy in Ontario: a population-based retrospective cohort study
      ICES in the News
      • Association between road traffic noise and incidence of diabetes mellitus and hypertension in Toronto, Canada: a population‐based cohort study
      • Increased risk of dementia among overactive bladder patients treated with an anticholinergic medication compared to a beta-3 agonist: a population-based cohort study
      • Canada and COVID-19: learning from SARS
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      • Increasing complexity of new nursing home residents in Ontario, Canada: a serial cross-sectional study
      • Intra-provincial variation in publicly funded mental health and addictions “services” use among Canadian Armed Forces families posted across Ontario
      • Benefits of high-volume medical oncology care for noncurable pancreatic adenocarcinoma: a population-based analysis
      • Assessing the impact of early identification of patients appropriate for palliative care on resource use and costs in the final month of life
      • Characterizing risk of type 2 diabetes in First Nations people living in First Nations communities in Ontario: a population-based analysis using cross-sectional survey data
      • Health system costs for cancer medications and radiation treatment in Ontario for the 4 most common cancers: a retrospective cohort study
      • Does physician compensation for declaration of involuntary status increase the likelihood of involuntary admission? A population-level cross-sectional linked administrative database study
      • Association of primary care involvement with death or hospitalizations for patients starting dialysis
    • May 2020

      • COVID-19 Laboratory Testing in Ontario: Patterns of Testing and Characteristics of Individuals Tested, as of April 30, 2020
      • Population-based estimates of health care utilization and expenditures by adults during the last 2 years of life in Canada’s single-payer health system
      • Association between traumatic brain injury and prison charges: a population-based cohort study
      • Five-year risk of admission to long-term care home and death for older adults given a new diagnosis of dementia: a population-based retrospective cohort study
      • Emergency department use by pregnant women in Ontario: a retrospective population-based cohort study
      ICES in the News
      • Inequity in access to transcatheter aortic valve replacement: a pan-Canadian evaluation of wait-times
      • Physician-based availability of psychotherapy in Ontario: a population-based retrospective cohort study
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      • An international cohort study of birth outcomes associated with hospitalized acute respiratory infection during pregnancy
      • Urban green space and the risks of dementia and stroke
      • Diabetes-induced eye disease among First Nations people in Ontario: a longitudinal, population-based cohort study
      • Association between immigration status and acute stroke care: a retrospective study
      • Long-term survival and costs following extracorporeal membrane oxygenation in critically ill children—a population-based cohort study
      • Use of sodium–glucose cotransporter-2 inhibitors and risk of acute kidney injury in older adults with diabetes: a population-based cohort study
      • Impact of stopping trastuzumab in early breast cancer: a population-based study in Ontario, Canada
      • Preterm birth, unplanned hospital contact, and mortality in infants born to teenage mothers in five countries: an administrative data cohort study
    • Universal drug coverage and income-related disparities in glycaemic control

      Branfield Day L, Austin PC, Shah BR. Diabet Med. 2020; 37(5):822-7. Epub 2019 Jun 14. DOI: 10.1111/dme.14051.

    • July 2020

      • Cost-effectiveness of investment in end-of-life home care to enable death in community settings
      • Association between palliative care and healthcare outcomes among adults with terminal non-cancer illness: population based matched cohort study
      ICES in the News
      • Predictors of suicide at time of diagnosis in schizophrenia spectrum disorder: a 20-year total population study in Ontario, Canada
      • COVID-19 Laboratory Testing in Ontario: Patterns of Testing and Characteristics of Individuals Tested, as of April 30, 2020
      • Effect of academic detailing on promoting appropriate prescribing of antipsychotic medication in nursing homes: a cluster randomized clinical trial
      • Geographic Variation in Primary Care Need, Service Use and Providers in Ontario, 2015/16
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      • Cardiac intervention rates for older patients with acute myocardial infarction in the United States and Ontario, 2003–2013: a retrospective cohort study
      • Variability in patient sociodemographics, clinical characteristics, and healthcare service utilization among 107,302 treatment seeking smokers in Ontario: a cross-sectional comparison
      • Primary care reform and funding equity for mental health disorders in Ontario: a retrospective observational population-based study
      • Validation of a type 1 diabetes algorithm using electronic medical records and administrative healthcare data to study the population incidence and prevalence of type 1 diabetes in Ontario, Canada
      • Clinical effectiveness of cardiac noninvasive diagnostic testing in outpatients evaluated for stable coronary artery disease
      • Early operative management in patients with adhesive small bowel obstruction: population-based cost analysis
      • Trends in very early discharge from hospital for newborns under midwifery care in Ontario from 2003 to 2017: a retrospective cohort study
      • Machine learning for identifying medication-associated acute kidney injury
    • Risk of severe maternal morbidity or death in relation to elevated hemoglobin A1c preconception, and in early pregnancy: a population-based cohort study

      Davidson AJF, Park AL, Berger H, Aoyama K, Harel Z, Cook JL, Ray JG. PLOS Med. 2020; 17(5):e1003104. Epub 2020 May 19. DOI:

    • January 2017

      • Marking 25 years of research impact
      • Living near major roads and the incidence of dementia, Parkinson's disease, and multiple sclerosis: a population-based cohort study
      • Inadequate screening for retinopathy among recent immigrants with type 2 diabetes despite universal health care: a population-based study
      Research video
      • Paul Kurdyak on ADHD rates and medication trends in Ontario
      ICES in the News
      • Variation in access to kidney transplantation across renal programs in Ontario, Canada
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      • Using the electronic medical record to identify patients at high risk for frequent ED visits and high system costs
      • Long-term clinical outcomes and predictors for survivors of out-of-hospital cardiac arrest
      • Effect of prepublication results on trends in prescribing of antihypertensive medication
      • Accounting for competing risks in randomized controlled trials: a review and recommendations for improvement
      • Outcomes of women and men with acute coronary syndrome treated with and without percutaneous coronary revascularization
    • November 2016

      • Risk of death from heart disease or cancer rises with either high or low HDL cholesterol
      • No worse outcomes seen after limit set on reimbursed diabetes test strips
      • ICES research video series: Tara Kiran on barriers to primary care reform for vulnerable patients
      • Gap closing on male, female life expectancy in Canada
      • More than 600 Ontarians died of opioid-related causes in 2013 with wide variation across the province
      • Study finds risk of hemorrhage with combination of two common statins and stroke prevention drug
      • Ontario Stroke Evaluation Report 2016: A Focus on Stroke Rehabilitation
      • Variability in antibiotic use across Ontario acute care hospitals
      • Recent temporal changes in atherosclerotic cardiovascular diseases in Ontario: clinical and health systems impact
      • Predictors of and trends in high-intensity end-of-life care among children with cancer: a population-based study using health services data
      • Prevalence, recurrence, and incidence of current depressive symptoms among people living with HIV in Ontario, Canada: results from the Ontario HIV Treatment Network Cohort Study
    • ICES–Métis Nation of Ontario Reports on Chronic Diseases

      Diabetes: Shah BR, Cauch-Dudek K, Wu CF. Cardiovascular Disease: Atzema CL, Kapral M, Klein-Geltink J, Asllani E. Cancer: Klein-Geltink J, Saskin R, Manno M, Urbach DR, Henry DA. Repiratory Disease: Klein-Geltink J, Khan S, Cascagnette P, Gershon G, To T, Crighton E, Henry DA, Pigeau L, MacQuarrie J, Allard Y, Burns B.  March 2012

    • Effect of prepublication results on trends in prescribing of antihypertensive medication: impact of the ALTITUDE (Aliskiren Trial in Type 2 Diabetes Using Cardio-Renal Disease Endpoints) trial on aliskiren prescribing

      Othman SS, Austin PC, Tu JV, Lee DS. Circ Cardiovasc Qual Outcomes. 2017; 10:e003152. Epub 2017 Jan 17.

    • May 2017

      • Emergency department as a first contact for mental health problems in children and youth
      • High rate of acute care use among people who use drugs
      • Low rate of cancer screening among transplant patients at heightened risk of cancer
      ICES in the News
      • Influence of environmental temperature on gestational diabetes risk
      • High rate of unnecessary antibiotic prescribing for seniors in Ontario
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      • Implementation and utilisation of telepsychiatry in Ontario: a population-based study
      • Population-based study to re-evaluate optimal lymph node yield in colonic cancer
      • Costs of cancer care in children and adolescents in Ontario, Canada
      • Trends in long-term mortality and morbidity in patients with no early complications after stroke and transient ischemic attack
      • Long-term outcomes of carotid endarterectomy versus stenting in a multicenter population-based Canadian study
      • Temporal trends in stroke incidence in South Asian, Chinese and white patients: a population based analysis
    • Ethnic differences in mental health and race-based data collection

      Chiu M. Healthc Q. 2017; 20(3):6-9.

    • Administrative data algorithms can describe ambulatory physician utilization

      Shah BR, Hux JE, Laupacis A, Zinman B, Cauch-Dudek K, Booth GL. Health Serv Res. 2007; 42(4):1783-96.

    • April 2019

      • Homelessness at discharge and its impact on psychiatric readmission and physician follow-up: a population-based cohort study
      • Glucose screening in pregnancy and future risk of cardiovascular disease in women: a retrospective, population-based study
      • Differences in HbA1C at the time of diabetes diagnosis in the adult population of Ontario, Canada
      • Incidence of heart failure among immigrants to Ontario, Canada: a CANHEART immigrant study
      ICES in the News
      • Do incentive payments reward the wrong providers? A study of primary care reform in Ontario, Canada
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      • The effect of adopting pediatric protocols in adolescents and young adults with acute lymphoblastic leukemia in pediatric vs adult centers: an IMPACT Cohort study
      • Patient-reported symptoms following mastectomy alone or lumpectomy plus radiation for early stage breast cancer: a cohort study
      • Impact of delisting high-strength opioid formulations from a public drug benefit formulary on opioid utilization in Ontario, Canada
      • Days at home in the last 6 months of life: a patient-determined quality indicator for cancer care
      • Periodic health visits by primary care practice model, a population-based study using health administrative data
    • June 2019

      • Naloxone Distribution Across Ontario
      • Neighborhood material deprivation is associated with childhood asthma development
      • End-of-career practice patterns of primary care physicians in Ontario
      • Quality of primary care among individuals receiving treatment for opioid use disorder
      ICES Research Video
      • Recent trends in child and youth emergency department visits because of pedestrian motor vehicle collisions by socioeconomic status in Ontario, Canada
      ICES in the News
      • Association between statin use and risk of dementia after a concussion
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      • Low-value diagnostic imaging use in the pediatric emergency department in the United States and Canada
      • Suicide in Canadian veterans living in Ontario: a retrospective cohort study linking routinely collected data
      • Ethnic differences in prediabetes incidence among immigrants to Canada: a population-based cohort study
      • The primary care and other health system use of home care patients: a retrospective cohort analysis
      • A population profile of older adults with prescription encounters with nurse practitioners and family physicians in Ontario: a descriptive retrospective cohort study
      • Derivation and external validation of a scoring system for predicting fracture risk after ischemic stroke in a Canadian cohort
    • Incretin based drugs and the risk of pancreatic cancer: international multicentre cohort study

      Azoulay L, Filion KB, Platt RW, Dahl M, Dormuth CR, Clemens KK, Durand M, Juurlink DN, Targownik LE, Turin TC, Paterson JM, Ernst P, Canadian Network for Observational Drug Effect Studies (CNODES) Investigators. BMJ. 2016; 352:i581.

    • How reliable are administrative data for capturing stroke patients and their care?

      Porter J, Mondor L, Kapral MK, Fang J, Hall RE. Cerebrovasc Dis Extra. 2016; 6(3):96-106. Epub 2016 Oct 18.

    • Risk factors for fracture in adult kidney transplant recipients

      Naylor KL, Zou G, Leslie WD, Hodsman AB, Lam NN, McArthur E, Fraser LA, Knoll GA, Adachi JD, Kim SJ, Garg AX. World J Transplant. 2016; 6(2):370-9. Epub 2016 Jun 24.

    • The association of dyslipidemia with chronic lymphocytic leukemia: a population-based study

      Mozessohn L, Earle C, Spaner D, Cheng SY, Kumar M, Buckstein R. J Natl Cancer Inst. 2017; 109(3):1-9. Epub 2016 Oct 17.

    • Association of temporal trends in risk factors and treatment uptake with coronary heart disease mortality, 1994-2005

      Wijeysundera HC, Machado M, Farahati F, Wang X, Witteman W, van der Velde G, Tu JV, Lee DS, Goodman SG, Petrella R, O'Flaherty M, Krahn M, Capewell S. JAMA. 2010; 303(18):1841-7.

    • Small-area variation in screening for cancer, glucose and cholesterol in Ontario: a cross-sectional study

      Fernandes KA, Sutradhar R, Borkhoff CM, Baxter N, Lofters A, Rabeneck L, Tinmouth J, Paszat L, Ontario Cancer Screening Research Network. CMAJ Open. 2015; 3(4):E1-9.

    • Serotonin-norepinephrine reuptake inhibitors and the risk of AKI: a cohort study of eight administrative databases and meta-analysis

      Renoux C, Lix LM, Patenaude V, Bresee LC, Paterson JM, Lafrance JP, Tamim H, Mahmud SM, Alsabbagh MW, Hemmelgarn B, Dormuth CR, Ernst P; Canadian Network of Observational Drug Effect Studies (CNODES) Investigators. Clin J Am Soc Nephrol. 2015; 10(10):1716-22. Epub 2015 Jul 31.

    • Comparative effectiveness of generic atorvastatin and Lipitor® in patients hospitalized with an acute coronary syndrome

      Jackevicius CA, Tu JV, Krumholz HM; Austin, PC, Ross JS, Stukel TA, Koh M, Chong A, Ko DT. J Am Heart Assoc. 2016; 5:e003350.

    • Those left behind from voluntary medical home reforms in Ontario, Canada

      Kiran T, Kopp A, Glazier RH. Ann Fam Med. 2016; 14(6):517:25.

    • Which risk factors are more associated with ischemic stroke than intracerebral hemorrhage in patients with atrial fibrillation?

      McGrath ER, Kapral MK, Fang J, Eikelboom JW, ó Conghaile A, Canavan M, O'Donnell MJ; Investigators of the Registry of the Canadian Stroke Network. Stroke. 2012; 43(8):2048-54. Epub 2012 May 22.

    • The CANHEART health index: a tool for monitoring the cardiovascular health of the Canadian population

      Maclagan LC, Park J, Sanmartin C, Mathur KR, Roth D, Manuel DG, Gershon A, Booth GL, Bhatia S, Atzema CL, Tu JV. CMAJ. 2014; 186(3):180-7. Epub 2013 Dec 23.

    • Temporal trends in cardiovascular disease risk factor profiles in a population-based schizophrenia sample: a repeat cross-sectional study

      Chiu M, Rahman F, Vigod S, Wilton AS, Kurdyak P. J Epidemiol Community Health. 2018; 72(1):71-7. Epub 2017 Oct 23.

    • Antipsychotic drug use in pregnancy: high dimensional, propensity matched, population based cohort study

      Vigod SN, Gomes T, Wilton AS, Taylor VH, Ray JG. BMJ. 2015; 350:h2298. Epub 2015 May 13.

    • Temporal trends in cardiovascular disease risk factors among white, South Asian, Chinese and black groups in Ontario, Canada, 2001 to 2012: a population-based study

      Chiu M, Maclagan LC, Tu JV, Shah BR. BMJ Open. 2015; 5:e007232.

    • Perinatal outcomes among women with bipolar disorder: a population-based cohort study

      Mei-Dan E, Ray JG, Vigod SN. Am J Obstet Gynecol. 2015; 212(3):367.e1-e8. Epub 2014 Oct 15.

    • Physical health and gender as risk factors for usage of services for mental illness

      Matheson FI, Smith KL, Fazli GS, Moineddin R, Dunn JR, Glazier RH. J Epidemiol Community Health. 2014; 68(10):971-8. Epub 2014 Jun 25.

    • Risk of hospitalization for community acquired pneumonia with renin-angiotensin blockade in elderly patients: a population-based study

      Shah S, McArthur E, Farag A, Nartey M, Fleet JL, Knoll GA, Kim SJ, Garg AX, Jain AK. PLoS One. 2014; 9(10):e110165. Epub 2014 Oct 29.

    • Trends in chronic disease incidence rates from the Canadian Chronic Disease Surveillance System

      Hamm NC, Pelletier L, Ellison J, Tennenhouse L, Reimer K, Paterson MJ, Puchtinger R, Bartholomew S, Phillips KAM, Lix LM. Health Promot Chronic Dis Prev Can. 2019; 39(6-7):216-24. Epub 2019 Jun 1. DOI: 10.24095/hpcdp.39.6/7.02.

    • The risk of heart failure and other cardiovascular hospitalizations after early stage breast cancer: a matched cohort study

      Abdel-Qadir H, Thavendiranathan P, Austin PC, Lee DS, Amir E, Tu JV, Fung K, Anderson GM. J Natl Cancer Inst. 2019; 111(8):854-62. Epub 2019 Jan 31. DOI: 10.1093/jnci/djy218.

    • Use of sodium–glucose cotransporter-2 inhibitors and risk of acute kidney injury in older adults with diabetes: a population-based cohort study

      Iskander C, Cherney DZ, Clemens KK, Dixon SN, Harel Z, Jeyakumar N, McArthur E, Muanda FT, Parikh CR, Paterson JM, Tangri N, Udell JA, Wald R, Garg AX. CMAJ. 2020; 192(14):E351-60. Epub 2020 Apr 6. DOI:

    • Smoking, drinking, diet and physical activity—modifiable lifestyle risk factors and their associations with age to first chronic disease

      Ng R, Sutradhar R, Zhan Y, Wodchis WP, Rosella L. Int J Epidemiol. 2020; 49(1):113-30. Epub 2019 Apr 26. DOI:

    • Primary care reform and funding equity for mental health disorders in Ontario: a retrospective observational population-based study

      Bayoumi I, Schultz SE, Glazier RH. CMAJ Open. 2020; 8(2):455-61. 2020; Jun 19 [Epub ahead of print]. DOI:

    • Sodium–glucose cotransporter-2 inhibitors and the risk for diabetic ketoacidosis: a multicenter cohort study

      Douros A, Lix LM, Fralick M, Dell’Aniello S, Shah BR, Ronksley PE, Tremblay E, Hu N, Alessi-Severini S, Fisher A, Bugden SC, Ernst P, Filion KB. Ann Intern Med. 2020; Jul 28 [Epub ahead of print]. DOI:

    • A population-based study of cardiovascular mortality following early-stage breast cancer

      Abdel-Qadir H, Austin PC, Lee DS, Amir E, Tu JV, Thavendiranathan P, Fung K, Anderson GM. JAMA Cardiol. 2017; 2(1):88-93. Epub 2016 Oct 12.

    • Association between incretin-based drugs and the risk of acute pancreatitis

      Azoulay L, Filion KB, Platt RW, Dahl M, Dormuth CR, Clemens KK, Durand M, Hu N, Juurlink DN, Paterson JM, Targownik LE, Turin TC, Ernst P, Suissa S, Hemmelgarn BR, Teare GF, Caetano P, Chateau D, Henry DA, LeLorier J, Levy AR, Sketris IS; Canadian Network for Observational Drug Effect Studies (CNODES) Investigators. JAMA Intern Med. 2016; 315(20):2211-20. Epub 2016 May 24.