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Publication Results (853)

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  • June 2020

    • Mood disorders in late life: a population-based analysis of prevalence, risk factors, and consequences in community-dwelling older adults in Ontario
    • Implementation of a physician incentive program for 18-month developmental screening in Ontario, Canada
    • Interventions supporting long term adherence and decreasing cardiovascular events after myocardial infarction (ISLAND): pragmatic randomised controlled trial
    ICES in the News
    • COVID-19 Laboratory Testing in Ontario: Patterns of Testing and Characteristics of Individuals Tested, as of April 30, 2020
    • Risk of hospitalization with hemorrhage among older adults taking clarithromycin vs azithromycin and direct oral anticoagulants
    • ICES’ new three-year strategic plan now available
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    • After-hours incentives and emergency department visits: evidence from Ontario
    • Identifying drugs with disease-modifying potential in Parkinson's disease using artificial intelligence and pharmacoepidemiology
    • In-hospital patient harm across linguistic groups: a retrospective cohort study of home care recipients
    • Healthcare costs and resource utilization associated with treatment of out-of-hospital cardiac arrest
    • Cancer staging in individuals with a severe psychiatric illness: a cross-sectional study using population-based cancer registry data
    • Treatment patterns and outcomes in adolescents and young adults with Hodgkin lymphoma in pediatric versus adult centers: an IMPACT cohort study
    • The impact of different antibiotic treatment regimens on mortality in Mycobacterium avium complex pulmonary disease (MAC-PD): a population-based cohort study
    • Association between the regional variation in premature mortality and immigration in Ontario, Canada
  • The impact of ductal carcinoma in situ on health services utilization

    Paszat L, Sutradhar R, Rakovitch E. Breast Cancer Res Treat. 2020; 182(1):159–68. Epub 2020 May 8. DOI:

  • Change in treatment modality and trends in survival among stage I non-small cell lung cancer patients: a population-based study

    Akhtar-Danesh GG, Finley C, Seow HY, Shakeel S, Akhtar-Danesh N. J Thorac Dis. 2020; Aug 1 [Epub ahead of print].

  • High-density lipoprotein cholesterol and cause-specific mortality in individuals without prior cardiovascular conditions: the CANHEART Study

    Ko DT, Alter DA, Guo H, Koh M, Lau G, Austin PC, Booth GL, Hogg W, Jackevicius CA, Lee DS, Wijeysundera HC, Wilkins JT, Tu JV. J Am Coll Cardiol. 2016; 68(19):2073-83. Epub 2016 Oct 31.

  • High-dose opioid prescribing and opioid-related hospitalization: a population-based study

    Spooner L, Fernandes K, Martins D, Juurlink D, Mamdani M, Paterson JM, Singh S, Gomes T. PLoS One. 2016; 11(12):e0167479.

  • March 2017

    • Use of medications of questionable benefit at the end of life in nursing home residents with advanced dementia
    • Risk of firearm injuries among children and youth of immigrant families
    • Early non-persistence with dabigatran and rivaroxaban in patients with atrial fibrillation
    Research video
    • Moira Kapral on risks of swallowing problems after stroke
    ICES in the News
    • Relationship between cardiac rehabilitation participation and health service expenditures within a universal health care system
    • Association of the timing of pregnancy with survival in women with breast cancer
    • Socioeconomic gradients in all-cause, premature and avoidable mortality among immigrants and long-term residents  
    • Failure of fertility therapy and subsequent adverse cardiovascular events
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    • Association between cardiovascular risk factors and aortic stenosis: the CANHEART aortic stenosis study
    • Infants born to opioid-dependent women in Ontario, 2002-2014
    • Mortality and costs of patients with community-onset Clostridium difficile infection identified using ED visits and hospital admissions
    • The relationship between therapeutic self-care and adverse events for home care clients in Ontario, Canada
    • Impact of unrestricted access to pregabalin on the use of opioids and other CNS-active medications
  • July 2016

    • Study of one million patients shows link between type 2 diabetes and many types of cancer
    • Home blood pressure monitoring may be driving unnecessary visits to ER
    • Concussion triples adult suicide risk, with rates highest following weekend concussions
    • Researchers find unexpected association between younger donor age, female sex and transfusion outcomes
    • New opioid use in adults with chronic obstructive pulmonary disease associated with increased risk of death
    • Study casts doubt on clinical significance of gadolinium brain deposits
    • First issue of Data and Discovery now available
    • Poorer children with diabetes have more adverse events using insulin pumps despite 24-hour support
    • Age, dementia, and long-term care residence are predictors of lower oral anticoagulant use for secondary stroke prevention
    • Older recipient age and female sex associated with increased fracture risk in kidney transplant recipients
  • ICES–Métis Nation of Ontario Reports on Chronic Diseases

    Diabetes: Shah BR, Cauch-Dudek K, Wu CF. Cardiovascular Disease: Atzema CL, Kapral M, Klein-Geltink J, Asllani E. Cancer: Klein-Geltink J, Saskin R, Manno M, Urbach DR, Henry DA. Repiratory Disease: Klein-Geltink J, Khan S, Cascagnette P, Gershon G, To T, Crighton E, Henry DA, Pigeau L, MacQuarrie J, Allard Y, Burns B.  March 2012

  • Waiting Lists for Radiation Therapy in Ontario

    Bondy S, Slaughter P, Przybysz R, Benk V, Hodgson D, Iscoe N, Paszat L, Laupacis A, Glazer D, Li C, Tucker W. December 2002

  • Variations in Quality Indicators Across Ontario Physician Networks

    Stukel TA, Croxford R, Rahman F, Bierman AS, Glazier RH. June 2016.

  • Cause-deleted health-adjusted life expectancy of Canadians with selected chronic conditions

    Manuel DG, Luo W, Ugnat AM, Mao Y. Chronic Dis Can. 2003; 24(4):108-15.

  • June 2017

    • The Mental Health of Children and Youth in Ontario: 2017 Scorecard
    • Two-thirds of Ontario hip fracture procedures are performed after hours
    • Playlist: ICES Mental Health & Addictions Research Symposium 2017
    ICES in the News
    • A 1980 letter on the risk of opioid addiction
    • Ontario and LHIN 2015/16 Stroke Report Cards and Progress Reports: Setting the Bar Higher
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    • Influences on the start, selection and duration of treatment with antibiotics in long-term care facilities
    • The impact of opioid medications on subsequent fractures in discharged emergency department patients with peripheral vertigo
    • Impact of immigration status on cancer outcomes in Ontario, Canada
    • Implementation and utilisation of telepsychiatry in Ontario: a population-based study
    • Impact of the publication of appropriate use criteria on utilization rates of myocardial perfusion imaging studies in Ontario, Canada: a population-based study
    • Adverse cardiac events associated with incident opioid drug use among older adults with COPD
    • Critical care at the end of life: a population-level cohort study of cost and outcomes
  • Preventing overdiagnosis: how to stop harming the healthy

    Moynihan R, Doust J, Henry D. BMJ. 2012; 344:e3502.

  • February 2018

    • People who receive physician visits at home in last year of life are less likely to die in hospital
    • 3 in 4 Ontarians hospitalized for psychiatric care are admitted involuntarily
      ICES in the News
      • Single fathers at increased risk of premature death, perhaps due to unhealthy lifestyle
      • Childhood cancer survivors found to be at higher risk of mental illness
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      • Patterns of methadone maintenance treatment provision in Ontario: Policy success or pendulum excess?
      • Health services burden of undiagnosed and overdiagnosed COPD
      • T-cell receptor excision circle levels and safety of paediatric immunization: a population-based self-controlled case series analysis
      • Association between newborn metabolic profiles and pediatric kidney disease
      • Association of polypharmacy with survival, complications and healthcare resource use after elective non-cardiac surgery: a population-based cohort study
      • Increasing incidence and prevalence of World Health Organization groups 1 to 4 pulmonary hypertension: a population-based cohort study in Ontario, Canada
      • Assessing covariate balance when using the generalized propensity score with quantitative or continuous exposures
    • Socioeconomic status and event free survival in pediatric acute lymphoblastic leukemia: a population-based cohort study

      Gupta S, Sutradhar R, Guttmann A, Sung L, Pole JD. Leuk Res. 2014; 38(12):1407-12. Epub 2014 Sep 1.

    • January 2019

      • Early initiation of palliative care is associated with reduced late-life acute-hospital use: a population-based retrospective cohort study
      • Cervical cancer screening access for women who experience imprisonment in Ontario, Canada
      • Effect of early physician follow-up on mortality and subsequent hospital admissions after emergency care for heart failure: a retrospective cohort study
      • Appropriate treatment receipt after breast-conserving surgery
      ICES in the News
      • Death and readmissions after hospital discharge during the December holiday period: cohort study
      • Incidence of cirrhosis in young birth cohorts in Canada from 1997 to 2016: a retrospective population-based study
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      • Evaluating the impact of prescribed versus nonprescribed benzodiazepine use in methadone maintenance therapy: results from a population-based retrospective cohort study
      • Overweight and obesity in preschool aged children and risk of mental health service utilization
      • Young stroke survivors with no early recurrence at high long‐term risk of adverse outcomes
      • Covariate-adjusted survival analyses in propensity-score matched samples: imputing potential time-to-event outcomes
      • A population-based study of the frequency and predictors of induced abortion among women with schizophrenia
    • Primary Care in Ontario: ICES Atlas

      Jaakkimainen L, Upshur REG, Klein-Geltink JE, Maaten S, Schultz SE, Leong A, Wang L, editors. November 2006

    • Arthritis and Related Conditions in Ontario: ICES Research Atlas. 2nd Edition

      Badley EM, Glazier RH, editors. September 2004

    • May 2019

      • Do-not-resuscitate and do-not-hospitalize orders in nursing homes: Who gets them and do they make a difference?
      • Nonsteroidal anti-inflammatory drug use and risk of acute kidney injury and hyperkalemia in older adults: a population-based study
      ICES in the News
      • Recent trends in child and youth emergency department visits because of pedestrian motor vehicle collisions by socioeconomic status in Ontario, Canada
      • Canada-wide health database to launch with federal funding
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      • Infective endocarditis hospitalizations and antibiotic prophylaxis rates before and after the 2007 American Heart Association guidelines revision
      • Trends in site of death and health care utilization at the end of life: a population-based cohort study
      • Cancer diagnosis and risk of suicide after accounting for prediagnosis psychiatric care: a matched‐cohort study of patients with incident solid‐organ malignancies
      • Predictors and variability of antibiotic prescribing amongst family physicians
      • The impact of the adoption of a patient rostering model on primary care access and continuity of care in urban family practices in Ontario, Canada
      • Comparing the high-dimensional propensity score for use with administrative data with propensity scores derived from high-quality clinical data
    • October 2019

      • Influenza vaccine effectiveness in preventing hospitalizations in older patients with chronic obstructive pulmonary disease
      • Association between physician intensity of antibiotic prescribing and the prescription of benzodiazepines, opioids and proton-pump inhibitors to nursing home residents: a population-based observational study
      • Cardiovascular consequences of obstructive sleep apnea in women: a historical cohort study
      ICES in the News
      • Prevalence of inappropriateness of parenteral vitamin B12 administration in Ontario, Canada
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      • One-year home-time and mortality after thrombolysis compared with nontreated patients in a propensity-matched analysis
      • Prescription synthetic oral cannabinoid use among older adults with chronic obstructive pulmonary disease: a population-based cohort study
      • Time trends in opioid prescribing among Ontario long-term care residents: a repeated cross-sectional study
      • Association of early-stage breast cancer and subsequent chemotherapy with risk of atrial fibrillation
      • An opioid prescription for men undergoing minor urologic surgery is associated with an increased risk of new persistent opioid use
      • Emergency department use in people who experience imprisonment in Ontario, Canada
      • Data variability across Canadian administrative health databases: differences in content, coding, and completeness
    • Using an alternative data source to examine randomization in the Canadian National Breast Screening Study

      Cohen MM, Kaufert PA, MacWilliam L, Tate RB. Clin Epidemiol. 1996; 49(9):1039-44.

    • Trends in health care utilization and costs attributable to hepatocellular carcinoma, 2002-2009: a population-based cohort study

      Thein HH, Qiao Y, Young SK, Zarin W, Yoshida EM, de Oliveira C, Earle CC. Curr Oncol. 2016; 23(3):e196-220. Epub 2016 Jun 9.

    • The association of dyslipidemia with chronic lymphocytic leukemia: a population-based study

      Mozessohn L, Earle C, Spaner D, Cheng SY, Kumar M, Buckstein R. J Natl Cancer Inst. 2017; 109(3):1-9. Epub 2016 Oct 17.

    • Sex differences in dose escalation and overdose death during chronic opioid therapy: a population-based cohort study

      Kaplovitch E, Gomes T, Camacho X, Dhalla IA, Mamdani MM, Juurlink D. PLoS One. 2015; 10(8):e0134550. Epub 2015 Aug 20.

    • Cohort profile: The ONtario Population Health and Environment Cohort (ONPHEC)

      Chen H, Kwong JC, Copes R, Villeneuve PJ, Goldberg MS, Ally SL, Weichenthal S, van Donkelaar A, Jerrett M, Martin RV, Brook JR, Kopp A, Burnett RT. Int J Epidemiol. 2016; 46(2):405-405j. Epub 2016 Apr 20.

    • Does increasing homecare nursing reduce emergency department visits at the end of life? A population-based cohort study of cancer decedents

      Seow H, Barbera L, Pataky R, Lawson B, O’Leary E, Fassbender K, McGrail K, Burge F, Brouwers M, Sutradhar R. J Pain Symptom Manage. 2016; 51(2):204-12. Epub 2015 Oct 26.

    • Temporal association between home nursing and hospital costs at end of life in three provinces

      Seow H, Pataky R, Lawson B, O’Leary EM, Sutradhar R, Fassbender K, McGrail K, Barbera L, Burge F, Peacock S, Hoch JS. Curr Oncol. 2016; 23(Suppl 1):S42-51. Epub 2016 Feb 29.

    • Those left behind from voluntary medical home reforms in Ontario, Canada

      Kiran T, Kopp A, Glazier RH. Ann Fam Med. 2016; 14(6):517:25.

    • Primary care screening and comorbidity management in rheumatoid arthritis in Ontario, Canada

      Widdifield J, Ivers NM, Bernatsky S, Jaakkimainen RL, Bombardier C, Thorne JC, Ahluwalia V, Paterson JM, Young J, Wing L, Tu K. Arthritis Care Res (Hoboken). 2017; 69(10):1495-1503. Epub 2016 Dec 20.

    • Methodological approaches to population based research of screening procedures in the presence of selection bias and exposure measurement error: colonoscopy and colorectal cancer outcomes in Ontario

      Jacob BJ, Sutradhar R, Moineddin R, Baxter NN, Urbach DR. BMC Med Res Methodol. 2013; 13:59. Epub 2013 Apr 24.

    • Differences in operative mortality between high- and low-volume hospitals in Ontario for 5 major surgical procedures: estimating the number of lives potentially saved through regionalization

      Urbach DR, Bell CM, Austin PC. CMAJ. 2003; 168(11):1409-14.

    • Cost-effectiveness analysis of potentially curative and combination treatments for hepatocellular carcinoma with person-level data in a Canadian setting

      Thein HH, Isaranuwatchai W, Qiao Y, Wong K, Sapisochin G, Chan KKW, Yoshida EM, Earle CC. Cancer Med. 2017; 6(9):2017-33. Epub 2017 Aug 8.

    • Association of high-density lipoprotein cholesterol with non-fatal cardiac and non-cardiac events: a CANHEART substudy

      Wijeysundera HC, Koh M, Alter DA, Austin PC, Jackevicius CA, Tu JV, Ko DT. Open Heart. 2017; 4(2):e000731. Epub 2017 Dec 17.

    • Palliative care delivery across health sectors: a population-level observational study

      Tanuseputro P, Budhwani S, Bai YQ, Wodchis WP. Palliat Med. 2017; 31(3):247-57. Epub 2016 Jun 16.

    • A population-based validation study of the DCIS Score predicting recurrence risk in individuals treated by breast-conserving surgery alone

      Rakovitch E, Nofech-Mozes S, Hanna W, Baehner FL, Saskin R, Butler SM, Tuck A, Sengupta S, Elavathil L, Jani PA, Bonin M, Chang MC, Robertson SJ, Slodkowska E, Fong C, Anderson JM, Jamshidian F, Miller DP, Cherbavaz DB, Shak S, Paszat L. Breast Cancer Res Treat. 2015; 152(2):389-98. Epub 2015 Jun 29.

    • Laparoscopic colorectal surgery in the emergency setting: trends in the province of Ontario

      Musselman RP, Gomes T, Chan BP, Auer RC, Moloo H, Mamdani M, Al-Omran M, Al-Obeed O, Boushey RP. Surg Laparosc Endosc Percutan Tech. 2015; 25(5):430-5. Epub 2015 Mar 19.

    • Predictors of diagnostic interval and associations with outcome in acute lymphoblastic leukemia

      Gupta S, Gibson P, Pole JD, Sutradhar R, Sung L, Guttmann A. Pediatr Blood Cancer. 2015; 62(6):957-63. Epub 2015 Jan 13.

    • Barriers to immediate breast reconstruction in the Canadian universal health care system

      Zhong T, Fernandes KA, Saskin R, Sutradhar R, Platt J, Beber BA, Novak CB, McCready DR, Hofer SO, Irish JC, Baxter NN. J Clin Oncol. 2014; 32(20):2133-41. Epub 2014 Jun 2.

    • A comprehensive assessment of family physician gender and quality of care: a cross-sectional analysis in Ontario, Canada

      Dahrouge S, Seale E, Hogg W, Russell G, Younger J, Muggah E, Ponka D, Mercer J. Med Care. 2016; 54(3):277-86. Epub 2016 Jan 13.

    • Place of care trajectories in the last two weeks of life: a population-based cohort study of Ontario decedents

      Qureshi D, Tanuseputro P, Perez R, Seow H. J Palliat Med. 2018; 21(11):1588-95. Epub 2018 Jul 16.