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Publication Results (207)

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  • Appropriate treatment receipt after breast-conserving surgery

    Guidolin K, Lock M, Vogt M, McClure JA, Winick-Ng J, Vinden C, Brackstone M. Curr Oncol. 2018; 25(6). Epub 2018 Dec 21.

  • Patient-reported symptoms following mastectomy alone or lumpectomy plus radiation for early stage breast cancer: a cohort study

    Davis LE, Fulton C, Bubis LD, Sussman J, Moody L, Barbera L, Li Q, Mahar AL, Coburn NG, Holloway CMB. Breast Cancer Res Treat. 2019; 175(3):721-31. Epub 2019 Mar 16. DOI: 10.1007/s10549-019-05196-x.

  • Statin exposure and risk of heart failure after anthracycline- or trastuzumab-based chemotherapy for early breast cancer: a propensity score-matched cohort study

    Abdel-Qadir H, Bobrowski D, Zhou L, Austin PC, Calvillo-Argüelles O, Amir E, Lee DS, Thavendiranathan P. J Am Heart Assoc. 2021; 10(2):e018393. Epub 2021 Jan 6. DOI:

  • Factors associated with endocrine therapy adherence among post-menopausal women treated for early-stage breast cancer in Ontario, Canada

    Blanchette PS, Lam M, Richard L, Allen B, Shariff SZ, Vandenberg T, Pritchard KI, Chan KKW, Louie AV, Desautels D, Raphael J, Earle CC. Breast Cancer Res Treat. 2020; 179(1):217-27. Epub 2019 Oct 1. DOI:

  • The association between endocrine therapy use and osteoporotic fracture among post-menopausal women treated for early-stage breast cancer in Ontario, Canada

    Blanchette PS, Lam M, Le B, Richard L, Shariff SZ, Ouedraogo AM, Pritchard KI, Raphael J, Vandenberg T, Fernandes R, Desautels DN, Chan KKW, Earle CC. Breast. 2021; 60:295-301. Epub 2021 Oct 30. DOI:

  • CT, MRI and ultrasound scanning rates: evaluation of cancer diagnosis, staging and surveillance in Ontario

    Coburn N, Przybysz R, Barbera L, Hodgson D, Sharir S, Laupacis A, Law C. J Surg Oncol. 2008; 98(7):490-9.

  • Bayesian synthesis using prior information on fracture risk from randomized trials to analyze post-market data

    John-Baptiste A, Becker T, Fung K, Lipscombe LL, Austin PC, Anderson GM. J Clin Epidemiol. 2018; 101:79-86. Epub 2018 Jun 4.

  • Depressive symptoms as a determinant of breast and cervical cancer screening in women: a population-based study in Ontario, Canada

    Vigod SN, Kurdyak PA, Stewart DE, Gnam WH, Goering PN. Arch Womens Ment Health. 2011; 14(2):159-68. Epub 2011 Feb 11.

  • Assessing the association of targeted therapy and intracranial metastatic disease

    Erickson AW, Habbous S, Wright F, Lofters AK, Jerzak KJ, Das S. JAMA Oncol. 2021; 7(8):1220-4. Epub 2021 Jun 3. DOI:

  • Multiple sclerosis and the cancer diagnosis: diagnostic route, cancer stage, and the diagnostic interval in breast and colorectal cancer

    Groome PA, Webber C, Maxwell CJ, McClintock C, Seitz D, Mahar A, Marrie RA. Neurology. 2022; 98(18):e1798-809. Epub 2022 Apr 28. DOI:

  • Modeling the longitudinal transitions of performance status in cancer outpatients: time to discuss palliative care

    Sutradhar R, Seow H, Earle C, Dudgeon D, Atzema C, Husain A, Howell D, Liu Y, Sussman J, Barbera L. J Pain Symptom Manage. 2013; 45(4):726-34. Epub 2012 Sep 3.

  • The risk of myocardial infarction with aromatase inhibitors relative to tamoxifen in post-menopausal women with early stage breast cancer

    Abdel-Qadir H, Amir E, Fischer HD, Fu L, Austin PC, Harvey PJ, Rochon PA, Lee DS, Anderson GM. Eur J Cancer. 2016; 68:11-21. Epub 2016 Sep 30.

  • Can chemotherapy-related acute care visits be accurately identified in administrative data?

    Krzyzanowska MK, Enright K, Moineddin R, Yun L, Powis M, Ghannam M, Grunfeld E. J Oncol Pract. 2018; 14(1):e51-8. Epub 2017 Nov 20.

  • Development and validation of a multivariable prediction model for major adverse cardiovascular events after early stage breast cancer: a population-based cohort study

    Abdel-Qadir H, Thavendiranathan P, Austin PC, Lee DS, Amir E, Tu JV, Fung K, Anderson GM. Eur. Heart J. 2019; 40(48):3913-20. Epub 2019 Jul 18. DOI: 10.1093/eurheartj/ehz460.

  • April 2016 *New design and format*

    Introducing a new design of At a Glance, using infographics, videos and news stories to share our research highlights.

    • Statins shown to be safe in generic form for high-risk coronary patients 
    • Ontarians' unhealthy behaviours cost $89.4 billion between 2004 and 2013
    • Adult prescriptions for ADHD drugs more than doubled in five years, but access uneven across Canada
    • Poor contraceptive practices are leading to pregnancies in users of isotretinoin, a drug that causes birth defects
    • Breast cancer patients receiving Herceptin treatment should be monitored for heart damage at any age
    • Women with schizophrenia less likely to use acute mental health services during pregnancy and after delivery
    • Dementia patients with multiple physicians or in long-term care at risk of medication conflict
  • Use of Large Bowel Procedures in Ontario

    Vinden C, Schultz S, Rabeneck L. February 2004

  • Remote, proactive, telephone based management of toxicity in outpatients during adjuvant or neoadjuvant chemotherapy for early stage breast cancer: pragmatic, cluster randomised trial

    Krzyzanowska MK, Julian JA, Gu C, Powis M, Li Q, Enright K, Howell D, Earle CC, Gandhi S, Rask S, Brezden-Masley C, Dent S, Hajra L, Freeman O, Spadafora S, Hamm C, Califaretti N, Trudeau M, Levine MN, Amir E, Bordeleau L, Chiarotto JA, Elser C, Husain J, Laferriere N, Rahim Y, Robinson AG, Vandenberg T, Grunfeld E. BMJ. 2021; 375:e066588. Epub 2021 Dec 8. DOI:

  • Comparative effectiveness and safety of pertuzumab and trastuzumab plus chemotherapy vs trastuzumab plus chemotherapy for treatment of metastatic breast cancer

    Dai WF, Beca JM, Nagamuthu C, Liu N, de Oliveira C, Earle CC, Trudeau M, Mercer RE, Chan KKW. JAMA Netw Open. 2022; 5(2):e2145460. Epub 2022 Feb 28. DOI:

  • Physicians' opinions about decision aids for patients considering systemic adjuvant therapy for axillary-node negative breast cancer

    O'Connor AM, Llewellyn-Thomas HA, Sawka C, Pinfold SP, To T, Harrison DE. Patient Educ Couns. 1997; 30(2):143-53.

  • A population-based case-cohort study of the risk of myocardial infarction following radiation therapy for breast cancer

    Paszat LF, Vallis KA, Benk VM, Groome PA, Mackillop WJ, Wielgosz A. Radiother Oncol . 2007; 82(3):294-300. Epub 2007 Feb 5.

  • Factors related to second cancer screening practice in disease-free cervical cancer survivors

    Park SM, Park CT, Park SY, Bae DS, Nam JH, Cho CH, Lee JM, Earle CC, Yun YH. Cancer Causes Control. 2009; 20(9):1697-703. Epub 2009 Aug 18.

  • Reduced screening mammography among women with diabetes

    Lipscombe LL, Hux JE, Booth GL. Arch Intern Med. 2005; 165(18):2090-5.

  • Waiting times for radiation therapy in Ontario

    Benk V, Przybysz R, McGowan T, Paszat L. Can J Surg. 2006; 49(1):16-21.

  • Short-term risk of cancer among women with previous gestational diabetes: a population-based study

    Bejaimal SA, Wu CF, Lowe J, Feig DS, Shah BR, Lipscombe LL. Diabet Med. 2016; 33(1):39-46. Epub 2015 May 13.

  • February 2019

    • Social licence and the general public’s attitudes toward research based on linked administrative health data, a qualitative study
    • Do doctors who order more routine medical tests diagnose more cancers? A population-based study from Ontario, Canada
    • Injection of opioids linked to increase in bacterial heart infections
    • Cause-specific mortality among HIV-infected people in Ontario, 1995–2014: a population-based retrospective cohort study
    • Association of surgical intervention for adhesive small-bowel obstruction with the risk of recurrence
    ICES in the News
    • How using your Ontario health card creates system change
    • Infertility treatment and risk of severe maternal morbidity: a propensity score-matched cohort study
    • Association of transvaginal mesh complications with the risk of new-onset depression or self-harm in women with a midurethral sling
    • Inflammatory bowel disease and new-onset psychiatric disorders in pregnancy and post-partum: a population based cohort study
    You may also be interested in...
    • The risk of heart failure and other cardiovascular hospitalizations after early stage breast cancer: a matched cohort study
    • One-year survival and admission to hospital for cardiovascular events among older residents of long-term care facilities who were prescribed intensive- and moderate-dose statins
    • Healthcare utilization costs of emerging adults with mood and anxiety disorders in an early intervention treatment program compared to a matched cohort
    • Survival and health care use after feeding tube placement in children with neurologic impairment
    • Disparities in breast cancer diagnosis for immigrant women in Ontario and BC: results from the CanIMPACT study
  • March 2021

    • Thank you to everyone who attended our virtual research symposium!
    • Association between anesthesiologist volume and short-term outcomes in complex gastrointestinal cancer surgery
    • Access to cancer surgery in a universal health care system during the COVID-19 pandemic
    • Factors associated with waiting time to breast cancer diagnosis among symptomatic breast cancer patients: a population-based study from Ontario, Canada
    • Mental Health and Addictions System Performance in Ontario: 2021 Scorecard
    ICES in the News
    • Comparison of palliative care delivery in the last year of life between adults with terminal noncancer illness or cancer
    • Testing, infection and complication rates of COVID-19 among people with a recent history of homelessness in Ontario, Canada: a retrospective cohort study
    • Shifts in office and virtual primary care during the early COVID-19 pandemic in Ontario, Canada
    • COVID-19 in Ontario: Notable findings for the week of March 7-13, 2021
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    • Does housing improve health care utilization and costs? A longitudinal analysis of health administrative data linked to a cohort of individuals with a history of homelessness
    • Overall health care cost during the year following diagnosis of colorectal cancer stratified by history of colorectal evaluative procedures
    • Injury-related deaths in the Ontario provincial trauma system: a retrospective population-based cohort analysis
    • Concordance between high antibiotic prescribing and high opioid prescribing among primary care physicians: a cross-sectional study
    • Health care costs associated with chronic hepatitis C virus infection in Ontario, Canada: a retrospective cohort study
    • Rates of rebleeding, thrombosis and mortality associated with resumption of anticoagulant therapy after anticoagulant-related bleeding
    • Association between continuity of care and subsequent diagnosis of multimorbidity in Ontario, Canada from 2001-2015: a retrospective cohort study
    • A population-based cohort study of respiratory disease and long-term exposure to iron and copper in fine particulate air pollution and their combined impact on reactive oxygen species generation in human lungs
  • March 2017

    • Use of medications of questionable benefit at the end of life in nursing home residents with advanced dementia
    • Risk of firearm injuries among children and youth of immigrant families
    • Early non-persistence with dabigatran and rivaroxaban in patients with atrial fibrillation
    Research video
    • Moira Kapral on risks of swallowing problems after stroke
    ICES in the News
    • Relationship between cardiac rehabilitation participation and health service expenditures within a universal health care system
    • Association of the timing of pregnancy with survival in women with breast cancer
    • Socioeconomic gradients in all-cause, premature and avoidable mortality among immigrants and long-term residents  
    • Failure of fertility therapy and subsequent adverse cardiovascular events
    You may also be interested in....
    • Association between cardiovascular risk factors and aortic stenosis: the CANHEART aortic stenosis study
    • Infants born to opioid-dependent women in Ontario, 2002-2014
    • Mortality and costs of patients with community-onset Clostridium difficile infection identified using ED visits and hospital admissions
    • The relationship between therapeutic self-care and adverse events for home care clients in Ontario, Canada
    • Impact of unrestricted access to pregabalin on the use of opioids and other CNS-active medications
  • August 2017

    • Prolonged standing on the job more likely to lead to heart attack than prolonged sitting
    • Antipsychotics common for adults with intellectual and developmental disabilities
    ICES Research Video Series
    • Rinku Sutradhar on opioid use in long-term cancer survivors
    ICES in the News
    • 1 in 5 opioid-related deaths in Ontario involve alcohol
    • Toward Quality Mental Health Services in Canada: a comparison of performance indicators across five provinces
    • Behind the prescriptions: A snapshot of opioid use across all Ontarians
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    • Predictors of obtaining follow-up care in the province of Ontario, Canada, following a new diagnosis of atrial fibrillation, heart failure, and hypertension in the emergency department
    • The variation of statin use among nursing home residents and physicians: a cross-sectional analysis
    • Cost-effectiveness analysis of potentially curative and combination treatments for hepatocellular carcinoma with person-level data in a Canadian setting
    • Lithium use, but not valproate use, is associated with a higher risk of chronic kidney disease in older adults with mental illness
    • A cross-sectional population-based study of breast cancer screening among women with HIV in Ontario, Canada
    • Association between operator specialty and outcomes after carotid artery revascularization
    • Costs of health care across primary care models in Ontario
  • January 2018

    Call for abstracts: IPDLN 2018 Conference
    • Diabetes risk in childhood cancer survivors: a population-based study
    • Association between handover of anesthesia care and adverse postoperative outcomes among patients undergoing major surgery
      ICES in the News
      • Acute myocardial infarction after laboratory-confirmed influenza infection
      • Effect of air quality alerts on human health: a regression discontinuity analysis in Toronto, Canada
      ICES Top 17 of '17
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      • Temporal trends in mental health service utilization across outpatient and acute care sectors: a population-based study from 2006 to 2014
      • The economic burden of cancer care in Canada: a population-based cost study
      • Elevated incidence of atrial fibrillation and stroke in patients with atrial flutter – a population-based study
      • The relation between food insecurity and mental health care service utilization in Ontario
      • Intergenerational abortion tendency between mothers and teenage daughters: population based cohort study
      • The impact of diabetes on breast cancer treatments and outcomes: a population-based study
      • Predictors of specialized pediatric palliative care involvement and impact on patterns of end-of-life care in children with cancer
    • May 2018

      September 2018 IPDLN Conference in Banff
      • Food insecurity more than doubles the risk of developing type 2 diabetes
      • Happiness linked to future health care costs
      • People with diabetes at increased risk for preventable complications after cancer diagnosis
      • Study identifies red flags for frontline providers when treating infants with bronchiolitis
        ICES in the News
        • Rates of whooping cough in Ontario much higher than previously thought
        • Nearly a quarter of all Ontarians newly prescribed opioids received a daily dose exceeding clinical guidelines
        • Study finds no link between HPV vaccination and risk of autoimmune disorders
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        • A population-based study of the risk of osteoporosis and fracture with dutasteride and finasteride
        • Unlocking First Nations health information through data linkage
        • Neighbourhood socioeconomic position and risks of major chronic diseases and all-cause mortality: a quasi-experimental study
        • Benchmarking time to initiation of end-of-life homecare nursing: a population-based cancer cohort study in regions across Canada
        • Factors associated with imaging in patients with early breast cancer after initial treatment
        • Association of clinical and economic outcomes with permanent pacemaker implantation after transcatheter aortic valve replacement
      • March 2019

        • Addressing Gaps in the Health Care Services Used by Adults with Developmental Disabilities in Ontario
        • Closed for business? Using a mixture model to explore the supply of psychiatric care for new patients
        • Association of duration of surgery with postoperative delirium among patients receiving hip fracture repair
        • Colorectal and breast cancer screening status for people in Ontario provincial correctional facilities
        • Exploring spatial variation in registration for deceased organ donation in Ontario, Canada
        ICES in the News
        • The impact of psychiatric utilisation prior to cancer diagnosis on survival of solid organ malignancies
        • Rural-urban differences in stroke risk factors, incidence, and mortality in people with and without prior stroke: the CANHEART Stroke Study
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        • Comparison of readmission and death among patients with cardiac disease in Northern vs Southern Ontario
        • Community-based specialist palliative care teams and health system costs at end of life: a retrospective matched cohort study
        • Equity and impact: Ontario’s infant rotavirus immunization program five years following implementation. A population-based cohort study
        • Evaluation of the fentanyl patch-for-patch program in Ontario, Canada
        • The association between insulin initiation and adverse outcomes after hospital discharge in older adults: a population-based cohort study
      • April 2019

        • Homelessness at discharge and its impact on psychiatric readmission and physician follow-up: a population-based cohort study
        • Glucose screening in pregnancy and future risk of cardiovascular disease in women: a retrospective, population-based study
        • Differences in HbA1C at the time of diabetes diagnosis in the adult population of Ontario, Canada
        • Incidence of heart failure among immigrants to Ontario, Canada: a CANHEART immigrant study
        ICES in the News
        • Do incentive payments reward the wrong providers? A study of primary care reform in Ontario, Canada
        You may also be interested in...
        • The effect of adopting pediatric protocols in adolescents and young adults with acute lymphoblastic leukemia in pediatric vs adult centers: an IMPACT Cohort study
        • Patient-reported symptoms following mastectomy alone or lumpectomy plus radiation for early stage breast cancer: a cohort study
        • Impact of delisting high-strength opioid formulations from a public drug benefit formulary on opioid utilization in Ontario, Canada
        • Days at home in the last 6 months of life: a patient-determined quality indicator for cancer care
        • Periodic health visits by primary care practice model, a population-based study using health administrative data
      • October 2019

        • Influenza vaccine effectiveness in preventing hospitalizations in older patients with chronic obstructive pulmonary disease
        • Association between physician intensity of antibiotic prescribing and the prescription of benzodiazepines, opioids and proton-pump inhibitors to nursing home residents: a population-based observational study
        • Cardiovascular consequences of obstructive sleep apnea in women: a historical cohort study
        ICES in the News
        • Prevalence of inappropriateness of parenteral vitamin B12 administration in Ontario, Canada
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        • One-year home-time and mortality after thrombolysis compared with nontreated patients in a propensity-matched analysis
        • Prescription synthetic oral cannabinoid use among older adults with chronic obstructive pulmonary disease: a population-based cohort study
        • Time trends in opioid prescribing among Ontario long-term care residents: a repeated cross-sectional study
        • Association of early-stage breast cancer and subsequent chemotherapy with risk of atrial fibrillation
        • An opioid prescription for men undergoing minor urologic surgery is associated with an increased risk of new persistent opioid use
        • Emergency department use in people who experience imprisonment in Ontario, Canada
        • Data variability across Canadian administrative health databases: differences in content, coding, and completeness
      • Using an alternative data source to examine randomization in the Canadian National Breast Screening Study

        Cohen MM, Kaufert PA, MacWilliam L, Tate RB. Clin Epidemiol. 1996; 49(9):1039-44.

      • Population-based assessment of emergency room visits and hospitalizations among women receiving adjuvant chemotherapy for early breast cancer

        Enright K, Grunfeld E, Yun L, Moineddin R, Ghannam M, Dent S, Eisen A, Trudeau M, Kaizer L, Earle C, Krzyzanowska MK. J Oncol Pract. 2015; 11(2):126-32. Epub 2015 Jan 20.

      • Disparities in receipt of screening tests for cancer, diabetes and high cholesterol in Ontario, Canada: a population-based study using area-based methods

        Borkhoff CM, Saskin R, Rabeneck L, Baxter NN, Liu Y, Tinmouth J, Paszat LF. Can J Public Health. 2013; 104(4):e284-90.

      • Trends in use and cost of initial cancer treatment in Ontario: a population-based descriptive study

        de Oliveira C, Bremner KE, Pataky R, Gunraj N, Haq M, Chan K, Cheung WY, Hoch JS, Peacock S, Krahn MD. CMAJ Open. 2013; 1(4):E151-8.

      • Setting quality improvement priorities for women receiving systemic therapy for early-stage breast cancer by using population-level administrative data

        Enright KA, Taback N, Powis ML, Gonzalez A, Yun L, Sutradhar R, Trudeau ME, Booth CM, Krzyzanowska MK. J Clin Oncol. 2017; 35(28):3207-14. Epub 2017 Jul 6.

      • Preventable diabetic complications after a cancer diagnosis in patients with diabetes: a population-based cohort study

        Worndl E, Fung K, Fischer HD, Austin PC, Krzyzanowska MK, Lipscombe LL. JNCI Cancer Spectr. 2018; 2(1):pky008. Epub 2018 May 11.

      • Barriers to immediate breast reconstruction in the Canadian universal health care system

        Zhong T, Fernandes KA, Saskin R, Sutradhar R, Platt J, Beber BA, Novak CB, McCready DR, Hofer SO, Irish JC, Baxter NN. J Clin Oncol. 2014; 32(20):2133-41. Epub 2014 Jun 2.