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Publication Results (180)

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  • Residential movement patterns of families of young children with chronic conditions in Ontario, Canada: a population-based cohort study

    Cohen E, Yantzi N, Guan J, Lam K, Guttmann A. Int J Equity Health. 2013; 12:62. Epub 2013 Aug 20.

  • The risk of mycobacterial infections associated with inhaled corticosteroid use

    Brode SK, Campitelli MA, Kwong JC, Lu H, Marchand-Austin A, Gershon AS, Jamieson FB, Marras TK. Eur Respir J. 2017; 50(3):1700037. Epub 2017 Sep 21.

  • December 2019

    • First Nations and Diabetes in Ontario
    • Validation study of health administrative data algorithms to identify individuals experiencing homelessness and estimate population prevalence of homelessness in Ontario, Canada
    • Association of baclofen with encephalopathy in patients with chronic kidney disease
    • Long-term mortality in mothers of infants with neonatal abstinence syndrome: a population-based parallel-cohort study in England and Ontario, Canada
    • Rates of recognized pregnancy in women with disabilities in Ontario, Canada
    • Dying of amyotrophic lateral sclerosis: health care use and cost in the last year of life
    ICES in the News
    • Long-term mental health outcomes in mothers and siblings of children with cancer: a population-based matched cohort study
    • Effect of asthma exacerbation during pregnancy in women with asthma: a population-based cohort study
    • Cross-Canada differences in early-stage breast cancer treatment and acute-care use
    • Population impact of generic valsartan recall
    • Trends of intentional drug overdose among youth: a population-based cohort study
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    • Interfacility patient sharing and clostridioides difficile infection incidence in the Ontario hospital system: a 13-year cohort study
    • The impact of air pollution on the incidence of diabetes and survival among prevalent diabetes cases
    • Comparison of cardiovascular risk factors and outcomes among practicing physicians vs the general population in Ontario, Canada
    • Real-world risk of cardiovascular outcomes associated with hypertriglyceridemia among individuals with atherosclerotic cardiovascular disease and potential eligibility for emerging therapies
    • Avoidable mortality rates decrease but inequity gaps widen for marginalized neighborhoods: a population-based analysis in Ontario, Canada from 1993 to 2014
  • Variation in low-value radiograph use for children in the emergency department: a cross-sectional study of administrative databases

    Freire GC, Diong C, Gandhi S, Saunders N, Neuman MI, Freedman SB, Friedman JN, Cohen E. CMAJ Open. 2022; 10(4):E889-99. Epub 2022 Oct 11. DOI:

  • Inhaled or systematic corticosteroids and the risk of hospitalizations for hip fracture among elderly women

    Lau E, Mamdani M, Tu K. Am J Med. 2003; 114(2):142-5.

  • April 2018

    Early bird registration and confirmed keynote speakers: 2018 IPDLN Conference
    • Low income, mental health needs put teens at higher risk for diabetes complications as adults
    • Ontario Stroke Evaluation Report 2018
      ICES in the News
      • Opioids linked to 1 in 6 deaths among young adults in Ontario
      ICES Research Video Series
      • Li Bai on diabetes, hypertension risk and exposure to ultrafine particles
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      • The use of electronic consultations is associated with lower specialist referral rates: a cross-sectional study using population-based health administrative data
      • Associations between neighborhood walkability and incident and ongoing asthma in children
      • Derivation and validation of a generalizable preoperative frailty index using population-based health administrative data
      • Refugee maternal and perinatal health in Ontario, Canada: a retrospective population-based study
      • Youth mental health services utilization rates after a large-scale social media campaign: population-based interrupted time-series analysis
      • Association between quality domains and health care spending across physician networks
    • June 2019

      • Naloxone Distribution Across Ontario
      • Neighborhood material deprivation is associated with childhood asthma development
      • End-of-career practice patterns of primary care physicians in Ontario
      • Quality of primary care among individuals receiving treatment for opioid use disorder
      ICES Research Video
      • Recent trends in child and youth emergency department visits because of pedestrian motor vehicle collisions by socioeconomic status in Ontario, Canada
      ICES in the News
      • Association between statin use and risk of dementia after a concussion
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      • Low-value diagnostic imaging use in the pediatric emergency department in the United States and Canada
      • Suicide in Canadian veterans living in Ontario: a retrospective cohort study linking routinely collected data
      • Ethnic differences in prediabetes incidence among immigrants to Canada: a population-based cohort study
      • The primary care and other health system use of home care patients: a retrospective cohort analysis
      • A population profile of older adults with prescription encounters with nurse practitioners and family physicians in Ontario: a descriptive retrospective cohort study
      • Derivation and external validation of a scoring system for predicting fracture risk after ischemic stroke in a Canadian cohort
    • Did changing primary care delivery models change performance? A population based study using health administrative data

      Jaakkimainen RL, Barnsley J, Klein-Geltink J, Kopp A, Glazier RH. BMC Fam Pract. 2011; 12:44.

    • The effect of a charted history of depression on emergency department triage and outcomes in patients with acute myocardial infarction

      Atzema CL, Schull MJ, Tu JV. CMAJ. 2011; 183(6):663-9. Epub 2011 Feb 28.

    • A cross-sectional, population-based study measuring comorbidity among people living with HIV in Ontario

      Kendall CE, Wong J, Taljaard M, Glazier RH, Hogg W, Younger J, Manuel DG. BMC Public Health. 2014; 14:161.

    • Physical health and gender as risk factors for usage of services for mental illness

      Matheson FI, Smith KL, Fazli GS, Moineddin R, Dunn JR, Glazier RH. J Epidemiol Community Health. 2014; 68(10):971-8. Epub 2014 Jun 25.

    • A population-based cohort study of respiratory disease and long-term exposure to iron and copper in fine particulate air pollution and their combined impact on reactive oxygen species generation in human lungs

      Zhang Z, Weichenthal S, Kwong JC, Burnett RT, Hatzopoulou M, Jerrett M, van Donkelaar A, Bai L, Martin RV, Copes R, Lu H, Lakey P, Shiraiwa M, Chen H. Environ Sci Technol. 2021; 55(6):3807-18. Epub 2021 Mar 5. DOI:

    • Chronic disease prevalence in women and air pollution: a 30-year longitudinal cohort study

      To T, Zhu J, Villeneuve PJ, Simatovic J, Feldman L, Gao C, Williams D, Chen H, Weichenthal S, Wall C, Miller AB. Environ Int. 2015; 80:26-32. Epub 2015 Apr 6.

    • Did emergency department visits in infants and young children increase in the last decade? An Ontario, Canada study

      To T, Terebessy E, Zhu J, Fong I, Liang J, Zhang K, McGihon R. Pediatr Emerg Care. 2022; 38(4):e1173-8. Epub 2021 Sep 23. DOI:

    • Combination long-acting beta-agonists and inhaled corticosteroids versus long-acting beta-agonists alone in older adults with chronic obstructive pulmonary disease

      Gershon AS, Campitelli MA, Croxford R, Stanbrook MB, To T, Upshur R, Stephenson A, Stukel TA. JAMA. 2014; 312(11):1114-21. Epub 2014 Sep 17.

    • Deliberate self-poisoning in Ontario following the terrorist attacks of September 11, 2001

      Detsky ME, Sivilotti ML, Kopp A, Austin PC, Juurlink DN. JAMA. 2005; 294(15):1900-1.

    • Are reductions in emergency department length of stay associated with improvements in quality of care? A difference-in-differences analysis

      Vermeulen MJ, Guttmann A, Stukel TA, Kachra A, Sivilotti ML, Rowe BH, Dreyer J, Bell R, Schull M. BMJ Qual Saf. 2016; 25(7):489-98. Epub 2015 Aug 13.

    • Canadian Veteran chronic disease prevalence and health services use in the five years following release: a matched retrospective cohort study using routinely collected data

      Mahar AL, St Cyr K, Enns JE, Aiken AB, Whitehead M, Cramm H, Kurdyak P. BMC Public Health. 2022; 22(1):1678. Epub 2022 Sep 5. DOI:

    • April 2017

      • Inflammatory bowel diseases on the rise in Canadian children
      • Low cancer screening rates among organ transplant patients in Ontario
      Research video
      • Baiju Shah on high thyroid cancer risk in Ontario immigrants from Southeast and East Asia
      ICES in the News
      • Two people a day die of opioid-related causes in Ontario
      • Many nursing home residents with dementia get medications of questionable benefit near the end of life
      • Where you live in Ontario could determine your risk of heart attack, stroke or dying of cardiovascular disease
      • No association between antidepressants during pregnancy and autism spectrum disorder in children
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      • Do people who experience incarceration age more quickly? Exploratory analyses using retrospective cohort data on mortality from Ontario, Canada
      • Mental health services claims and adult onset asthma in Ontario, Canada
      • Impact of a provincial quality-improvement program on primary health care in Ontario: a population-based controlled before-and-after study
      • The association of frailty with outcomes and resource use after emergency general surgery: a population-based cohort study
      • Level of need, divertibility, and outcomes of newly admitted nursing home residents
      • The Cardiovascular Health in Ambulatory Care Research Team performance indicators for the primary prevention of cardiovascular disease: a modified Delphi panel study
    • Development of measures of the quality of emergency department care for children using a structured panel process

      Guttmann A, Razzaq A , Lindsay P, Zagorski B, Anderson GM. Pediatrics. 2006; 118(1):114-23.

    • Relationship between social inequalities and ambulatory care-sensitive hospitalizations persists for up to 9 years among children born in a major Canadian urban center

      Agha MM, Glazier RH, Guttmann A. Ambul Pediatr. 2007; 7(3):258-62.

    • Association of anti-smoking legislation with rates of hospital admission for cardiovascular and respiratory conditions

      Naiman A, Glazier RH, Moineddin R. CMAJ. 2010; 182(8):761-7. Epub 2010 Apr 12.

    • Herpes zoster as a marker of underlying malignancy

      Iglar K, Kopp A, Glazier RH. Open Med. 2013; 7(2):e68-73. Epub 2013 Jun 18.

    • October 2017

      • Chronic Obstructive Pulmonary Disease in Ontario
      • Impact of pneumococcal vaccination on pneumonia hospitalizations and related costs in Ontario
      • Gabapentin, opioids and the risk of opioid-related death

      ICES Research Video
      • Natasha Saunders on study showing one-third lower risk of suicide or self-harm among immigrant children and youth
      ICES in the News
      • Antipsychotics common for adults with intellectual and developmental disabilities
      • Association between immigrant status and end-of-life care in Ontario, Canada
      • Effectiveness of a financial incentive to physicians for timely follow-up after hospital discharge
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      • Impact of restricting diagnostic imaging reimbursement for uncomplicated low back pain in Ontario: a population-based interrupted time series analysis
      • Temporal trends in cardiovascular disease risk factor profiles in a population-based schizophrenia sample: a repeat cross-sectional study
      • Comparative safety of direct oral anticoagulants and warfarin in venous thromboembolism: multicentre, population based, observational study
      • False-positive newborn screening for cystic fibrosis and health care use
      • Economic impact of subsequent depression in patients with a new diagnosis of stable angina: a population-based study
      • Are we Choosing Wisely in lymphoma? Excessive use of surveillance CT imaging in patients with diffuse large B-cell lymphoma (DLBCL) in long-term remission
      • Real-world health care utilization and effectiveness of omalizumab for the treatment of severe asthma
      • Effect of preoperative geriatric evaluation on outcomes after elective surgery: a population-based study
    • November 2017

      Call for abstracts: IPDLN 2018 Conference
      • Two-thirds of children with concussions not receiving medical follow-ups
      • People with developmental disabilities and mental illness have twice the risk of hospital readmissions
      • Inhaled corticosteroids do not increase risk of fracture in children with asthma
      • People with mental illness or addictions have higher health care needs and costs
      ICES in the News
      • Hip fracture surgery after more than 24 hours associated with increased risk of death and other complications
      • Direct medical costs of motorcycle crashes in Ontario
      • Flu vaccine prevents hospitalization in children
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      • Big data and population health: focusing on the health impacts of the social, physical, and economic environment
      • Indigenous health data and the path to healing
      • Derivation and external validation of prediction models for advanced chronic kidney disease following acute kidney injury
      • Ethnic differences in mental health and race-based data collection
      • Predicting psychiatric readmission: sex-specific models to predict 30-day readmission following acute psychiatric hospitalization
      • The medical care of male and female youth who die by suicide: a population-based case control study
      • Mortality in infants affected by preterm birth and severe small-for-gestational age birth weight
      • Increased coronary heart disease and stroke hospitalisations from ambient temperatures in Ontario
      • Changes in the dispensing of opioid medications in Canada following the introduction of a tamper-deterrent formulation of long-acting oxycodone
      • Variations in use of optimal medical therapy in patients with nonobstructive coronary artery disease

    • Using a linked data set to determine the factors associated with utilization and costs of family physician services in Ontario: effects of self-reported chronic conditions

      Iron KS, Manuel DG, Williams J. Chronic Dis Can. 2003; 24(4):124-32.

    • Clinical predictors of multiple tympanostomy tube placements in Ontario children

      Beyea JA, Nguyen P, Hall SF Laryngoscope. 2018; 128(4):991-7. Epub 2017 Sep 12.

    • November 2018

      • Many Ontario youths not receiving timely follow-up after first emergency visit for psychotic disorder
      • Blood lithium monitoring practices in a population-based sample of older adults
      • Prevalence of severe maternal morbidity and factors associated with maternal mortality in Ontario, Canada
      ICES Research Video Trailer
      • Mortality and chronic disease risk associated with poor life satisfaction: a population-based cohort study
      ICES in the News
      • Cancer in First Nations People in Ontario: Incidence, Mortality, Survival and Prevalence
      • Maternal intellectual or developmental disability and newborn discharge to protective services
      • Screening for a new primary cancer in patients with existing metastatic cancer: a retrospective cohort study
      • Mental health outcomes after major trauma in Ontario: a population-based analysis
      • Comparative risk of harm associated with trazodone or atypical antipsychotic use in older adults with dementia
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      • Pilot study of the ability to probabilistically link clinical trial patients to administrative data and determine long-term outcomes
      • Describing the process of ethical conduct of research in an Ontario-wide First Nations diabetes research project
      • Patient engagement in a trial testing a new strategy of acute heart failure care
      • Generational patterns of asthma incidence among immigrants to Canada over two decades: a population-based cohort study
      • Influence of surgical procedures and general anesthesia on child development before primary school entry among matched sibling pairs
      • Regional variation in healthcare spending and mortality among senior high-cost healthcare users in Ontario, Canada: a retrospective matched cohort study
      • High health care costs among adults with intellectual and developmental disabilities: a population based study
    • Direct health-care costs for children diagnosed with genetic diseases are significantly higher than for children with other chronic diseases

      Marshall DA, Benchimol EI, MacKenzie A, Duque DR, MacDonald KV, Hartley T, Howley H, Hamilton A, Gillespie M, Malam F, Boycott KM. Genet Med. 2019; 21(5):1049-57. Epub 2018 Sep 24.
    • Inpatient smoking-cessation counseling and all-cause mortality in patients with acute myocardial infarction

      Van Spall HG, Chong A, Tu JV. Am Heart J. 2007; 154(2):213-20.

    • November 2020

      • Life expectancy and health-adjusted life expectancy in people with inflammatory bowel disease
      • Utilisation and outcomes of allogeneic hematopoietic cell transplantation in Ontario, Canada, and New York State, USA: a population-based retrospective cohort study
      • Patient-centered time-at-home outcomes in older adults after surgical cancer treatment
      ICES in the News
      • COVID-19 in Ontario: Notable findings for the week of November 1-7, 2020
      • Prenatal hepatitis B screening, and hepatitis B burden among children, in Ontario: a descriptive study
      • Association between adherence to fractional flow reserve treatment thresholds and major adverse cardiac events in patients with coronary artery disease
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      • Incidental detection, imaging modalities and temporal trends of differentiated thyroid cancer in Ontario: a population-based retrospective cohort
      • The associations between direct and delayed critical care unit admission with mortality and readmissions among patients with heart failure
      • Increasing wait-time mortality for severe aortic stenosis: a population-level study of the transition in practice from surgical aortic valve replacement to transcatheter aortic valve replacement
      • Declining use of red blood cell transfusions for gastrointestinal cancer surgery: a population-based analysis
      • Regional health care services and rates of lower extremity amputation related to diabetes and peripheral artery disease: an ecological study
      • Use of cardiac noninvasive testing after emergency department discharge: association of hospital network testing intensity and outcomes in Ontario, Canada
      • Comorbidities before and after the diagnosis of rheumatoid arthritis: a matched longitudinal study
      • Coexistence of clinically significant obstructive sleep apnea with physician-diagnosed asthma or chronic obstructive pulmonary disease: a population study of prevalence and mortality
    • Identifying children and youth with autism spectrum disorder in electronic medical records: examining health system utilization and comorbidities

      Brooks JD, Bronskill SE, Fu L, Saxena FE, Arneja J, Pinzaru VB, Anagnostou E, Nylen K, McLaughlin J, Tu K. Autism Res. 2021; 14(2):400-10. Epub 2020 Oct 24. DOI:

    • May 2021

      • Variable impact of COVID-19 on urgent intervention in Ontario
      • Comparison of childhood asthma incidence in 3 neighbouring cities in southwestern Ontario: a 25‑year longitudinal cohort study
      • Suicide and self-harm in adult survivors of critical illness: population based cohort study
      • Delay of pregnancy among physicians vs nonphysicians
      ICES in the News
      • Individual and social determinants of SARS-CoV-2 testing and positivity in Ontario, Canada: a population-wide study
      • Perinatal outcomes during the COVID-19 pandemic in Ontario, Canada
      • COVID-19 in Ontario: Highlights for the week of May 2–8, 2021
      • Association between bariatric surgery and major adverse diabetes outcomes in patients with diabetes and obesity
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      • Risk factors for outbreaks of SARS-CoV-2 infection at retirement homes in Ontario, Canada: a population-level cohort study
      • The requirement for surgery and subsequent 30-day mortality in patients with COVID-19
      • Is coronavirus disease 2019 associated with indicators of long-term bladder dysfunction?
      • Sex differences in multimorbidity and polypharmacy trends: a repeated cross-sectional study of older adults in Ontario, Canada
      • Health care utilization in medically complex people living with HIV before and after admission to an HIV-specific community facility: a pre–post comparison study
      • Health care costs of rheumatoid arthritis: a longitudinal population study
      • Health care utilisation and costs associated with different treatment protocols for newly diagnosed childhood acute lymphoblastic leukaemia: a population-based study in Ontario, Canada
      • Derivation and validation of a two-variable index to predict 30-day outcomes following heart failure hospitalization
    • June 2021

      • Postpartum mental illness during the COVID-19 pandemic: a population-based, repeated cross-sectional study
      • Association of socioeconomic status with medical assistance in dying: a case-control analysis
      • Inequities in access to primary care among opioid recipients in Ontario, Canada: a population-based cohort study
      • Development and validation of a machine learning model using administrative health data to predict onset of type 2 diabetes
      ICES in the News
      • A population-based analysis of the impact of the COVID-19 pandemic on common abdominal and gynecological emergency department visits
      • COVID-19 in Ontario: Highlights for the week of June 6–12, 2021
      • Adherence at 2 years with distribution of essential medicines at no charge: the CLEAN Meds randomized clinical trial
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      • Stroke care and case fatality in people with and without schizophrenia: a retrospective cohort study
      • Childhood food insecurity and incident asthma: a population-based cohort study of children in Ontario, Canada
      • Lung cancer inequalities in stage of diagnosis in Ontario, Canada
      • Patterns of cardiovascular risk factors in the years before pregnancy in nulliparous women with and without preterm birth and small-for-gestational-age delivery
      • Association between end-of-life cancer care and immigrant status: a retrospective cohort study in Ontario, Canada
      • Primary care-based smoking cessation treatment and subsequent healthcare service utilisation: a matched cohort study of smokers using linked administrative healthcare data
      • Morbidity and mortality reduction associated with polysomnography testing in idiopathic pulmonary fibrosis: a population-based cohort study
      • Glycemic control in transition-aged versus early adults with type 1 diabetes and the effect of a government-funded insulin pump program
    • July 2021

      • Surgery and the subtype of inflammatory bowel disease impact the risk of venous thromboembolism after hospital discharge
      • Primary care provider and child characteristics associated with age of diagnosis of autism spectrum disorder: a population-based cohort study
      • Risk of serious medical events in patients with depression treated with electroconvulsive therapy: a propensity score-matched, retrospective cohort study
      ICES in the News
      • Development and validation of a predictive algorithm for risk of dementia in the community setting
      • Predicting death in home care users: derivation and validation of the Risk Evaluation for Support: Predictions for Elder-Life in the Community Tool (RESPECT)
      • Prevalence of winter migration to warmer destinations among Ontarians (“snowbirds”) and patterns of their use of health care services: a population-based analysis
      • COVID-19 in Ontario: Highlights for the week of July 4-10, 2021
      • Effectiveness of COVID-19 vaccines against variants of concern, Canada
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      • Measuring the impact of the COVID-19 pandemic on organized cancer screening and diagnostic follow-up care in Ontario, Canada: a provincial, population-based study
      • Effect of a health system payment and quality improvement programme for tonsillectomy in Ontario, Canada: an interrupted time series analysis
      • Depression-related weight change and incident diabetes in a community sample
      • Health services use by children identified as heterozygous hemoglobinopathy mutation carriers via newborn screening
      • Characteristics and outcomes of women developing heart failure after early stage breast cancer chemotherapy: a population-based matched cohort study
      • Childhood seizures after prenatal exposure to maternal influenza infection: a population-based cohort study from Norway, Australia and Canada
      • Specialist care in individuals with asthma who required hospitalization: a retrospective population-based study
      • NAFLD and alcohol-related liver disease will be responsible for almost all new diagnoses of cirrhosis in Canada by 2040
    • Predictors of postoperative complications in vestibular schwannoma surgery-a population-based study

      Alkins RD, Newsted D, Nguyen P, Campbell RJ, Beyea JA. Otol Neurotol. 2021; 42(7):1067-73. Epub 2021 Mar 5. DOI:

    • August 2021

      • COVID-19 positivity rates, hospitalizations and mortality of adults with and without intellectual and developmental disabilities in Ontario, Canada
      • SARS-CoV-2 infection among maternal-infant dyads in Ontario, Canada
      • Acute care visits for assault and maltreatment before vs during the COVID-19 pandemic in Ontario, Canada
      ICES in the News
      • Comparison of medication prescribing before and after the COVID-19 pandemic among nursing home residents in Ontario, Canada
      • Sociodemographic changes in emergency department visits due to alcohol during COVID-19
      • COVID-19 in Ontario
      • Preterm birth and stillbirth rates during the COVID-19 pandemic: a population-based cohort study
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      • Association between dementia care programs in assisted living facilities and transitions to nursing homes in Ontario, Canada: a population-based cohort study
      • Impact of changes in opioid funding and clinical policies on rapid tapering of opioids in Ontario, Canada
      • Effect of smoke-free legislation on respiratory health services use in children with asthma: a population-based open cohort study in Ontario, Canada
      • High prevalence of comorbidities at diagnosis in immigrants with multiple sclerosis
      • Days alive and at home after hip fracture: a cross-sectional validation of a patient-centred outcome measure using routinely collected data
      • Early invasive coronary angiography and acute ischaemic heart failure outcomes
      • Regional variation in the potentially inappropriate first-line use of fluoroquinolones in Canada as a key to antibiotic stewardship? A drug utilization review study
      • Background rates of all-cause mortality, hospitalizations, and emergency department visits among nursing home residents in Ontario, Canada to inform COVID-19 vaccine safety
    • Visualizing and forecasting the association of air quality and health outcomes in Ontario, Canada

      Liang S, Zhu J, McGihon R, Terebessy E, Ge E, Su Y, Fong I, To T. Can Geogr. 2021; 65(3):382-9. Epub 2021 Jan 13. DOI:

    • Factors associated with nonreceipt of recommended COPD medications: a population study

      Gershon AS, Pequeno P, Alberga Machado A, Aaron SD, Kendzerska T, Luo J, Stanbrook MB, Tan WC, Porter J, To T. Chest. 2021; 160(5):1670-80. Epub 2021 Jun 15. DOI:

    • Beyond the grey tsunami: a cross-sectional population-based study of multimorbidity in Ontario

      Ryan BL, Bray Jenkyn K, Shariff SZ, Allen B, Glazier RH, Zwarenstein M, Fortin M, Stewart M. Can J Public Health. 2018; 109(5-6):845-54. Epub 2018 Jul 18.