Publication Results (70)

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• Why are implantable cardioverter defibrillator outcomes in practice different from clinical trials?

  Krishnakumar N, Tu JV, Lee DS. Card Electrophysiol Clin. 2011; 3(4):511-20. Epub 2011 Sep 26.

• Reporting of gender-related information in clinical trials of drug therapy for myocardial infarction

  Rochon PA, Clark JP, Binns MA, Patel V, Gurwitz JH. CMAJ. 1998; 159(4):321-27.

• The inclusion of minority groups in clinical trials: problems of under-representation and under-reporting of data

  Rochon PA, Mashari A, Cohen A, Misra A, Laxer D, Streiner DL, Clark JP, Dergal JM, Gold J. Account Res. 2004; 11(3-4):215-23.

• Representation of patients with dementia in clinical trials of donepezil

  Gill SS, Bronskill SE, Mamdani M, Sykora K, Li P, Shulman KI, Anderson GM, Hillmer MP, Wodchis WP, Rochon PA. Can J Clin Pharmacol. 2004; 11(2):e274-85. Epub 2004 Dec 15.

• The application of disease management to clinical trial designs

  Puterman J, Alter DA. Popul Health Manag. 2009; 12(4):205-8.

• July/August 2006

  • Significant proportion of Ontario cancer patients have poor quality end-of-life care
  • Clinical trials that use acronyms are cited more often
  • Study identifies performance measures for emergency department care for children
  • ICES report presents in-depth look at primary care across the life-cycle
  • Landmark report examines influence of geography on heart disease patients across Canada

• March 2005

  • Internationally trained doctors provide same level of heart attack care as Canadian physicians
  • U.S. cancer centers of excellence have lower surgical mortality, but same long-term survival rates
  • Diabetic patients with poor blood sugar control could be better managed
  • Aging "baby boomers" will increase need for life support in ICUs
  • Clinical trials of Alzheimer’s drug do not adequately represent patients taking it

• Februrary 2005

  • Blueprint for children’s health services needed in Ontario
  • SSRIs do not increase risk of digoxin toxicity
  • Minorities under represented in clinical trials
  • Surgeon specialty and volume impacts outcomes in patients undergoing surgery for lung cancer
  • Single data source could help improve heart attack care in Canada

• June 2004

  • Use of anti-inflammatory drugs associated with greater risk of hospitalization for heart failure
  • Patients should see hospital physicians after discharge
  • Leading causes of global death and disability not being studied in clinical trials
  • Many common illnesses increase risk of suicide in elderly
  • Most deaths in men with prostate cancer not due to prostate cancer

• Prescriptions for estrogen replacement therapy in Ontario before and after publication of the Women's Health Initiative study

  Austin PC, Mamdani MM, Tu K, Jaakkimainen L. JAMA. 2003; 289(24):3241-2.

• The fall and rise of carotid endarterectomy in the United States and Canada

  Tu JV, Hannan EL, Anderson GM, Iron K, Wu K, Vranizan K, Popp AJ, Grumbach K. N Engl J Med. 1998; 339(20):1441-7.

• Problems for clinical judgement: introducing cognitive psychology as one more basic science

  Redelmeier DA, Ferris LE, Tu JV, Hux JE, Schull MJ. CMAJ. 2001; 164(3):358-60.

• Acronym-named Randomized Trials in medicine - the ART in medicine study

  Stanbrook MB, Austin PC, Redelmeier DA. N Engl J Med. 2006; 355(1):101-2.

• Adoption of adjuvant chemotherapy for non–small-cell lung cancer: a population-based outcomes study

  Booth CM, Shepherd FA, Peng Y, Darling GE, Li G, Kong W, Mackillop WJ. J Clin Oncol. 2010; 28(21):3472-8. Epub 2010 Jun 21.

• Major trauma in elderly adults receiving lipid-lowering medications

  Redelmeier DA, Naylor CD, Brenneman FD, Sharkey PW, Juurlink DN. J Trauma. 2001; 50(4):678-83.

• Economic evaluations in the Canadian Common Drug Review

  Laupacis A. Pharmacoeconomics. 2006; 24(11):1157-62.

• Persistence with therapy among patients treated with warfarin for atrial fibrillation

  Gomes T, Mamdani MM, Holbrook AM, Paterson JM, Juurlink DN. Arch Intern Med. 2012; 172(21):1687-9. Epub 2012 Oct 22.

• Persistence with bisphosphonate therapy in older people

  Melo M, Qiu F, Sykora K, Juurlink D, Laupacis A, Mamdani M. J Am Geriatr Soc. 2006; 54(6):1015-6.

• Rates of hemorrhage during warfarin therapy for atrial fibrillation

  Gomes T, Mamdani MM, Holbrook AM, Paterson JM, Hellings C, Juurlink DN. CMAJ. 2013; 185(2):E121-7. Epub 2012 Nov 26.

• Pilot study of the ability to probabilistically link clinical trial patients to administrative data and determine long-term outcomes

  Hay AE, Pater JL, Corn E, Han L, Camacho X, O'Callaghan C, Chong N, Bell EN, Tu D, Earle CC. Clin Trials. 2019; 16(1):14-7. Epub 2018 Nov 22.

• Healthcare resource utilization and costs among patients with direct oral anticoagulant or warfarin-related major bleeding

  Xu Y, Schulman S, Dowlatshahi D, Holbrook AM, Simpson CS, Shepherd LE, Wells PS, Giulivi A, Gomes T, Mamdani M, Frymire E, Khan S, Johnson AP; Bleeding Effected by Direct Oral Anticoagulants (BLED-AC) Study Group. Thromb Res. 2019; 182:12-9. Epub 2019 Aug 2. DOI: 10.1016/j.thromres.2019.07.026.

• One-year survival and admission to hospital for cardiovascular events among older residents of long-term care facilities who were prescribed intensive- and moderate-dose statins

  Campitelli MA, Maxwell CJ, Maclagan LC, Ko DT, Bell CM, Jeffs L, Morris AM, Lapane KL, Daneman N, Bronskill SE. CMAJ. 2019; 191(2):E32-9. Epub 2019 Jan 24. DOI: 10.1503/cmaj.180853.

• The relevance of subgroup-specific treatment effects: the Studies Of Left Ventricular Dysfunction (SOLVD) revisited

  Parker AB, Yusuf S, Naylor CD. Am Heart J. 2002; 144(6):941-7.

• Routine utilization of glycoprotein IIb/IIIa inhibitor therapy is associated with improved in-hospital outcome after percutaneous coronary intervention: insights from a large prospective single-centre registry

  Jackevicius CA, Pinto R, Daly P, Mackie K, Dzavik V. Can J Cardiol. 2005; 21(1):27-32.

• The rapid uptake of concurrent chemotherapy for cervix cancer patients treated with curative radiation

  Barbera L, Paszat L, Thomas G, Covens A, Fyles A, Elit L, Qiu F. Int J Radiat Oncol Biol Phys. 2006; 64(5):1389-94. Epub 2006 Jan 18.

• The effect of emergency department crowding on clinically oriented outcomes

  Bernstein SL, Aronsky D, Duseja R, Epstein S, Handel D, Hwang U, McCarthy M, John McConnell K, Pines J, Rathlev N, Schafermeyer R, Zwemer F, Schull M, Asplin BR; Society for Academic Emergency Medicne, Emergency Department Crowding Task Force. Acad Emerg Med. 2009; 16(1):1-10. Epub 2008 Nov 8.

• The effect of computerized physician order entry with clinical decision support on the rates of adverse drug events: a systematic review

  Wolfstadt JI, Gurwitz JH, Field TS, Lee M, Kalkar S, Wu W, Rochon PA. J Gen Intern Med. 2008; 23(4):451-8.

• Pediatric hodgkin lymphoma: maximizing efficacy and minimizing toxicity

  Hodgson DC, Hudson MM, Constine LS. Semin Radiat Oncol. 2007; 17(3):230-42.

• Systematic review of strategies to measure HIV-related diarrhea

  Tinmouth J, Kandel G, Tomlinson G, Walmsley S, Steinhart HA, Glazier R. HIV Clin Trials. 2007; 8(3):155-63.

• Thirty-day in-hospital revascularization and mortality rates after acute myocardial infarction in seven Canadian provinces

  Johansen H, Brien SE, Fines P, Bernier J, Humphries K, Stukel TA, Ghali WA; Canadian Cardiovascular Outcomes Research Team. Can J Cardiol. 2010; 26(7):e243-8.

• Changing trends in rectal cancer surgery in Ontario: 2002–2009

  Musselman RP, Gomes T, Chan BP, Auer RC, Moloo H, Mamdani M, Al-Omran M, Al-Obeed O, Boushey RP. Colorectal Dis. 2012; 14(12):1467-72. Epub 2012 Nov 15.

• Preoperative statin use and postoperative acute kidney injury

  Brunelli SM, Waikar SS, Bateman BT, Chang TI, Lii J, Garg AX, Winkelmayer WC, Choudry NK. Am J Med. 2012; 125(12):1195-1204. Epub 2012 Oct 10.

• Oral bisphosphonate use in the elderly is not associated with acute kidney injury

  Shih AW, Weir MA, Clemens KK, Yao Z, Gomes T, Mamdani MM, Juurlink DN, Hird A, Hodsman A, Parikh CR, Wald R, Cadarette SM, Garg AX. Kidney Int. 2012; 82(8):903-8. Epub 2012 Jun 13.

• Determinants of outcome after carotid endarterectomy

  Kucey DS, Bowyer B, Iron K, Austin P, Anderson G, Tu JV. J Vasc Surg. 1998; 28(6):1051-8.

• Adherence with statin therapy in elderly patients with and without acute coronary syndromes

  Jackevicius CA, Mamdani M, Tu JV. JAMA. 2002; 288(4):462-7.

• Effectiveness of statins for secondary prevention in elderly patients after acute myocardial infarction: an evaluation of class effect

  Zhou Z, Rahme E, Abrahamowicz M, Tu JV, Eisenberg MJ, Humphries K, Austin PC, Pilote L. CMAJ. 2005; 172(9):1187-94.

• Factors explaining the under-use of reperfusion therapy among ideal patients with ST-segment elevation myocardial infarction

  Alter DA, Ko DT, Newman A, Tu JV. Eur Heart J. 2006; 27(13):1539-49. Epub 2006 Jun 7.

• Effectiveness and safety of drug-eluting stents in Ontario

  Tu JV, Bowen J, Chiu M, Ko DT, Austin PC, He Y, Hopkins R, Tarride JE, Blackhouse G, Lazzam C, Cohen EA, Goeree R. N Engl J Med. 2007; 357(14):1393-402.

• Estimate of the benefits of a population-based reduction in dietary sodium additives on hypertension and its related health care costs in Canada

  Joffres MR, Campbell NR, Manns B, Tu K. Can J Cardiol. 2007; 23(6):437-43.

• Perioperative chemotherapy for muscle-invasive bladder cancer: a population-based outcomes study

  Booth CM, Siemens DR, Li G, Peng Y, Tannock IF, Kong W, Berman DM, Mackillop WJ. Cancer. 2014; 120(11):1630-8. Epub 2014 Apr 14.

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