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Socioeconomic status and event free survival in pediatric acute lymphoblastic leukemia: a population-based cohort study

Gupta S, Sutradhar R, Guttmann A, Sung L, Pole JD. Leuk Res. 2014; 38(12):1407-12. Epub 2014 Sep 1.


The impact of socioeconomic status (SES) upon childhood cancer outcomes has not been extensively examined. Our objective was to determine the association between SES and event-free survival (EFS) among children with acute lymphoblastic leukemia (ALL) diagnosed in Ontario, Canada from 1995-2011 (N=1541) using Cox proportional hazards. Neither neighborhood-level median income quintile, distance from tertiary center, or rural residence significantly predicted EFS in the context of a universal healthcare system. Immigrant children experienced significantly superior EFS; confounding by ethnicity could not be ruled out. Confirmatory studies using additional individual-level SES variables are warranted.

Keywords: Cancer Pediatric health Social determinants of health

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