View by Topic

Information for Scientists

Aboriginal People (10)

Asthma (50)

Cancer (185)

Cardiovascular (444)

Continuity of Care (28)

Decision-Making (53)

Diabetes (146)

Diagnostic Testing (74)

Drugs (394)

Emergency Services (122)

Ethics (10)

Geriatrics (173)

Health Economics (73)

Health Human Resources (54)

Health Policy (135)

Health Technology Assessment (22)

Home Care (20)

Mental Health (86)

Methods (155)

Miscellaneous/Other (20)

Performance Measurement (49)

Population Health (117)

Primary Care (156)

Privacy (6)

Resource Utilization (109)


	View publications
	\|

Methods

A brief note on overlapping confidence intervals

A Canadian comparison of data sources for coronary artery bypass surgery outcome 'report cards'

A comparison of a Bayesian vs. a frequentist method for profiling hospital performance

A comparison of Bayesian methods for profiling hospital performance

A comparison of methods for analyzing health-related quality-of-life measures

A comparison of propensity score methods: a case-study estimating the effectiveness of post-AMI statin use

A comparison of regression trees, logistic regression, generalized additive models, and multivariate adaptive regression splines for predicting AMI mortality

A comparison of statistical learning methods on the GUSTO database

A comparison of the ability of different propensity score models to balance measured variables between treated and untreated subjects: a Monte Carlo study

A comparison of the statistical power of different methods for the analysis of cluster randomization trials with binary outcomes

A critical appraisal of propensity score matching in the medical literature between 1996 and 2003

A data-generation process for data with specified risk differences or numbers needed to treat

A modification of the Elixhauser comorbidity measures into a point system for hospital death using administrative data

A multicenter study of the coding accuracy of hospital discharge administrative data for patients admitted to cardiac care units in Ontario

A population-based risk algorithm for the development of diabetes: development and validation of the Diabetes Population Risk Tool (DPoRT)

A simplified, oninvasive stool DNA test for colorectal cancer detection

A substantial and confusing variation exists in handling of baseline covariates in randomized controlled trials: a review of trials published in leading medical journals

A tutorial and case study in propensity score analysis: An application to estimating the effect of in-hospital smoking cessation counseling on mortality

A tutorial on methods to estimating clinically and policy-meaningful measures of treatment effects in prospective observational studies

Absolute risk reductions and numbers needed to treat can be obtained from adjusted survival models for time-to-event outcomes

Absolute risk reductions, relative risks, relative risk reductions, and numbers needed to treat can be obtained from a logistic regression model

Accuracy of administrative databases in identifying patients with hypertension

Acronym-named Randomized Trials in medicine: the ART in medicine study

Administrative data accurately identified intensive care unit admissions in Ontario

Administrative data algorithms can describe ambulatory physician utilization

Administrative database research has unique characteristics that can risk biased results

Age-social stratification designs had a negligible impact on income-mortality associations

An introduction to multilevel regression models

An overview of the methods and data used in the CCORT Canadian Cardiovascular Atlas project

Analysis of interval-censored data from clustered multistate processes: application to joint damage in psoriatic arthritis

Analysis of observational studies in the presence of treatment selection bias

Are (the log-odds of) hospital mortality rates normally distributed? Implications for studying variations in outcomes of medical care

Assessing balance in measured baseline covariates when using many-to-one matching on the propensity-score

At A Glance - July/August 2006

Automated variable selection methods for logistic regression produced unstable models for predicting acute myocardial infarction mortality

Balance diagnostics for comparing the distribution of baseline covariates between treatment groups in propensity-score matched samples

Bayesian extensions of the Tobit model for analyzing measures of health status

Bayesian modeling of missing data in clinical research

Bayesian propensity score analysis for observational data

Bayesian statistical inference enhances the interpretation of contemporary randomized controlled trials

Bayeswatch: an overview of Bayesian statistics

Bias in penalized quasi-likelihood estimation in random effects logistic regression models when the random effects are not normally distributed

Boosted classification trees result in minor to modest improvement in the accuracy in classifying cardiovascular outcomes compared to conventional classification trees

Bootstrap methods for developing predictive models in cardiovascular research

Bootstrap model selection had similar performance for selecting authentic and noise variables compared to backward variable elimination: a simulation study

Can the health utilities index measure change?

Canadian Institute for Health Information Discharge Abstract Database: a validation study

Cardiovascular health and services in Ontario

Comparative ability of comorbidity classification methods for administrative data to predict outcomes in patients with chronic obstructive pulmonary disease

Comparing clinical data with administrative data for producing AMI report cards

Comparing hierarchical modelling with traditional logistic regression analysis among patients hospitalized with acute myocardial infarction: should we be analyzing cardiovascular outcomes data differently?

Comparing methods to calculate hospital-specific rates of early death or urgent readmission

Comparison of coding of heart failure and comorbidities in administrative and clinical data for use in outcomes research

Conditioning on the propensity score can result in biased estimation of common measures of treatment effect: a Monte Carlo study

Confounders and intermediaries in case-control study designs: A strategy for distinguishing between the two when measured using the same variable

Confronting the confounders: the meaning, detection, and treatment of confounders in research

Covariate balance in a Bayesian propensity score analysis of beta blocker therapy in heart failure patients

Cross-cultural comparisons of health status in Canada using the health utilities index

Data-driven comparisons of binary proportions between levels of a categorical variable can result in incorrect statistical significance levels

Defining needs-based urban health planning areas is feasible and desirable: a population-based approach in Toronto, Ontario

Design and implementation of a population-based registry of implantable cardioverter defibrillators (ICDs) in Ontario

Development and preliminary psychometric testing of a new OA pain measure – an OARSI/OMERACT initiative

Development of an algorithm to identify preoperative medical consultations using administrative data

Diabetes in Ontario: determination of prevalence and incidence using a validated administrative data algorithm

Differences between systematic reviews and health technology assessments: a trade-off between the ideals of scientific rigor and the realities of policy making

Effect of population-based interventions on laboratory utilization: a time-series analysis

Effectiveness of preprocedural statin therapy on clinical outcomes for patients with stable coronary artery disease after percutaneous coronary interventions

Estimating gestational age at birth: A population-based derivation-validation study

Estimating linear regression models in the presence of a censored independent variable

Estimating multilevel logistic regression models when the number of clusters is low: a comparison of different statistical software procedures

Evaluating the effectiveness of 2 educational interventions in family practice

Evaluating the performance of the GRACE risk-adjustment index across socioeconomic strata among patients discharged from the hospital after AMI

Focus groups in health services research at ICES

Forecasting the need for dialysis services in Ontario, Canada to 2011

Generating survival times to simulate Cox proportional hazards models with time-varying covariates

GEOGLE: context mining tool for the correlation between gene expression and the phenotypic distinction

Goodness-of-fit diagnostics for the propensity score model when estimating treatment effects using covariate adjustment with the propensity score

Health systems research training enhances workplace research skills: a qualitative evaluation

Health technology assessment in critical care

How many people have had a myocardial infarction? Prevalence estimated using historical hospital data

How well is the clinical importance of study results reported? An assessment of randomized controlled trials

ICD-10 adaptations of the Ontario acute myocardial infarction mortality prediction rules performed as well as the original versions

Identifying patients with ischemic heart disease in an electronic medical record

Impact of the choice of benchmark on the conclusions of hospital report cards

Improving population attributable fraction methods: examining smoking-attributable mortality for 87 geographic regions in Canada

Indicators of quality of care for patients with acute myocardial infarction

Inflation of the type I error rate when a continuous confounding variable is categorized in logistic regression analyses

Inflation of Type I error rate in multiple regression when independent variables are measured with error

Interpreting the concordance statistic of a logistic regression model: Relation to the variance and odds ratio of a continuous explanatory variable

Introducing a methodology for estimating duration of surgery in health services research

Introduction to the Canadian Cardiovascular Outcomes Research Team's (CCORT) Canadian Cardiovascular Atlas project

Living and dying in Ontario: an opportunity to improve health information

Logistic regression had superior performance compared with regression trees for predicting in-hospital mortality in patients hospitalized with heart failure

Making trials matter: pragmatic and explanatory trials and the problem of applicability

Measurement properties of the activities scale for kids

Measuring population health: correlates of the Health Utilities Index among English and French Canadians

Measuring the health burden of chronic disease and injury using health adjusted life expectancy and the Health Utilities Index

Methodological challenges in evaluating mobile crisis psychiatric programs

Myocardial infarction and the validation of physician billing and hospitalization data using electronic medical records

Nursing time devoted to medication administration in long-term care: clinical, safety, and resource implications

Optimal Bayesian probability levels for hospital report cards

Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies

Optimal statistical decisions for hospital report cards

Parents were accurate proxy reporters of urgent pediatric asthma health services—a retrospective agreement analysis

Pisces did not have increased heart failure: data-driven comparisons of binary proportions between levels of a categorical variable can result in incorrect statistical significance levels

Predicting post-discharge death or readmission: deterioration of model performance in population having multiple admissions per patient

Predictive accuracy study: comparing a statistical model to clinicians' estimates of outcomes after coronary bypass surgery

Primer on statistical interpretation or methods report card on propensity-score matching in the cardiology literature from 2004 to 2006

Propensity-score matching in the cardiovascular surgery literature from 2004 to 2006: a systematic review and suggestions for improvement

Quality assessment of administrative data (QuAAD): an opportunity for enhancing Ontario's health data

Quality of hospital discharge and physician data for type of breast cancer surgery

Quantifying the impact of survivor treatment bias in observational studies

Quantile regression: a statistical tool for out-of-hospital research

R and S-PLUS produced different classification trees for predicting patient mortality

Readers should systematically assess methods used to identify, measure and analyze confounding in observational cohort studies

Registry of the Canadian Stroke Network: Progress Report 2001-2005

Relation between randomized controlled trials published in leading general medical journals and the global burden of disease

Reporting of numerical and statistical differences in abstracts: improving but not optimal

Reporting randomized, controlled trials of herbal interventions: an elaborated CONSORT statement

Safety and effectiveness of drug-eluting stents among diabetic patients: a propensity analysis

Self-reported use of mental health services versus administrative records: care to recall?

Self-reported use of mental health services versus administrative records: should we care?

Some methods of propensity-score matching had superior performance to others: results of an empirical investigation and Monte Carlo simulations

Statistical criteria for selecting the optimal number of untreated subjects matched to each treated subject when using many-to-one matching on the propensity score

Study design to determine the effects of widespread restrictions on hospital utilization to control an outbreak of SARS in Toronto, Canada

Testing multiple statistical hypotheses resulted in spurious associations: a study of astrological signs and health

The Cochrane Collaboration – how is it progressing?

The consistency of panelists' appropriateness ratings: do experts produce clinically logical scores for rectal cancer treatment?

The derivation of life tables for local areas

The effect of a hepatitis serology testing algorithm on laboratory utilization

The effectiveness of interprofessional education: key findings from a new systematic review

The impact of undercoding of cardiac severity and comorbid diseases on the accuracy of hospital report cards

The impact of unmeasured clinical variables on the accuracy of hospital report cards: a Monte Carlo study

The inclusion of minority groups in clinical trials: problems of under-representation and under-reporting of data

The large-sample performance of backwards variable elimination

The performance of different propensity score methods for estimating marginal odds ratios

The performance of different propensity-score methods for estimating differences in proportions (risk differences or absolute risk reductions) in observational studies

The performance of different propensity-score methods for estimating relative risks

The performance of two data-generation processes for data with specified marginal treatment odds ratios

The relationship between the c-statistic of a risk-adjustment model and the accuracy of hospital report cards: A Monte Carlo study

The relative ability of different propensity score methods to balance measured covariates between treated and untreated subjects in observational studies

The use of quantile regression in health care research: a case study examining gender differences in the delivery of thrombolysis

The use of the propensity score for estimating treatment effects: administrative versus clinical data

The use of the Tobit model for analyzing measures of health status

Users' guides to the medical literature: how to use an article about mortality in a humanitarian emergency

Using administrative databases to measure waiting times for patients undergoing major cancer surgery in Ontario, 1993–2000

Using linked health administrative data to assess the clinical and healthcare system impact of chronic diseases in Ontario

Using methods from the data-mining and machine-learning literature for disease classification and prediction: a case study examining classification of heart failure subtypes

Using the bootstrap to improve estimation and confidence intervals for regression coefficients selected using backwards variable elimination

Using the Johns Hopkins Aggregated Diagnosis Groups (ADGs) to predict mortality in a general adult population cohort in Ontario, Canada

Using the standardized difference to compare the prevalence of a binary variable between two groups in observational research

Variation in the days supply field for osteoporosis medications in Ontario

Varied definitions of hospital volume did not alter the conclusions of volume-outcome analyses

Volume 5, No 1 of informed - December 1998 [571 KB PDF]

Volume 6, No 3 of informed - June 2000 [410 KB PDF]

Information for Scientists