Daniel I McIsaac

Senior Adjunct Scientist (Full Status) ICES uOttawa Primary Care & Health Systems Research Program

Biography

Dan McIsaac is an anesthesiologist and scientist with a focus on perioperative process improvement and intervention research with the goal of improving patient outcomes and health system efficiency. This focus is pursued through population-based health services and epidemiologic research, as well as prospective evaluation of interventions in high-risk perioperative patients. Dan's specific interests include frailty, healthcare quality and safety, and patient-reported outcome measures.

MPH, Quantitative Research Methods, Harvard School of Public Health
FRCPC, Anesthesiology
MD, Dalhousie University

Surgery
Outcomes research
Geriatrics and aging
Health services research

Associate Scientist, Ottawa Hospital Research Institute
Research Chair, Perioperative Health Systems and Outcomes Research, University of Ottawa
Associate Professor, Department of Anesthesiology and Pain Medicine, University of Ottawa
Anesthesiologist, The Ottawa Hospital

ICES Grants

Grant

2021 - 2023

STRIVE before surgery trial: a vanguard pragmatic multicenter randomized trial of Structured TRaining to Improve fitness in a Virtual Environment before surgery

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Gillis CA, Hallet J, Kidd GD, McIsaac DI, Mcneely ML, Taljaard M, Tandon P, Wijeysundera DN
Co-Investigators: Auer RAC, Boland LS, Breau RH, Bryson GL, Chesney T, Eskander A, Fergusson DA, Forster AJ, Gagné S, Gill M, Hladkowicz E, Khadaroo R, Lalu MM, Lavallée LT, Martel G, McCartney CJ, Moloo H, Roberts DJ, Scheede-Bergdahl C, Serrano PF, Thavorn K, Van Walraven C, Vogt KN, Zwarenstein MF
Grant Type: Project Grant
Grant Amount: $260,100

Grant

2019 - 2023

PREPARE Trial: a parallel arm multicenter randomized trial of frailty-focused PReoperative Exercise to decrease PostoperAtive complication Rates and disability scorEs

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Fegusson DA, Khadaroo R, McIsaac DI, Muscedere J, Taljaard M
Co-Investigators: Boet S, Boland LS, Breau RH, Bryson GL, Caycedo A, Eskander A, Forster AJ, Gagné S, Holroyd-Leduc JM, Huang AR, Johnson A, Lalu MM, Lavallée LT, Ma G, Mccartney CJ, Mcelhaney JE, Moloo H, Nagpal S, Nantel J, Power BE, Saha T, Scheede-Bergdahl C, Thavorn K, Van Walraven C, Wijeysundera D
Grant Type: Project Grant
Grant Amount: $1,136,025

Grant

2019 - 2021

Safe Analgesia For Elders receiving Peripheral Nerve Blocks for hip fracture (SAFE PNB)

Granting Agency: Canadian Institutes of Health Research
Principal Investigators: Forster AJ, McIsaac DI, van Walraven C
Co-Investigators: Abdallah FW, Beaule PE, Boet S, Fernando SM, Huang AR, McCartney CJ, Meulenkamp B, Perry JJ, Power BE, Ramlogan R, Taljaard M, Tanuseputro P, Wijeysundera DN
Grant Type: Project Grant
Grant Amount: $183,600

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Awards & Recognition

01/06/2016

Junior Research Chair in Perioperative Health Systems and Outcomes Research

2016: Awarded to Dr. Daniel I McIsaac by the University of Ottawa Faculty of Medicine.

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Journal Articles

Journal Article

26/02/2024

A quasi-experimental evaluation of the association between implementation of Quality-Based Procedures funding for hip fractures and improvements in processes and outcomes for hip fracture patients in Ontario: an interrupted time series analysis

Zhang HY, Ramlogan RR, Talarico R, Grammatopolous G, Papp S, McIsaac DI. Can J Anaesth. 2024; Feb 26 [Epub ahead of print].

Journal Article

02/09/2023

Association of preoperative anaesthesia consultation prior to elective noncardiac surgery with patient and health system outcomes: a population-based study

Engel JS, Beckerleg W, Wijeysundera DN, Aucoin S, Leblanc J, Gagne S, Bryson GL, Lalu MM, Wyand A, McIsaac DI. Br J Anaesth. 2023; Sep 2 [Epub ahead of print].

Journal Article

01/06/2023

Association between opioid prescription profiles and adverse health outcomes in opioid users referred for sleep disorder assessment: a secondary analysis of health administrative data

Kendzerska T, Malhotra A, Gershon AS, Povitz M, McIsaac DI, Aaron SD, Bryson GL, Talarico R, Godbout M, Tanuseputro P, Chung F. Front Sleep. 2023; 2:1161857. Epub 2023 Jun 1.

Journal Article

09/05/2023

Association between the COVID-19 pandemic and first cancer treatment modality: a population-based cohort study

Fu R, Sutradhar R, Li Q, Hanna TP, Chan KKW, Irish JC, Coburn N, Hallet J, Dare A, Singh S, Parmar A, Earle CC, Lapointe-Shaw L, Krzyzanowska MK, Finelli A, Louie AV, Look Hong NJ, Witterick IJ, Mahar A, Urbach DR, McIsaac DI, Enepekides D, Eskander A. CMAJ Open. 2023; 11(3):E426-33. Epub 2023 May 9.

Journal Article

31/03/2023

Early survival for patients newly diagnosed with cancer during COVID-19 in Ontario, Canada: a population-based cohort study

Fu R, Sutradhar R, Li Q, Kalraj P, Dare A, Hanna TP, Chan KKW, Irish JC, Coburn N, Hallet J, Singh S, Parmar A, Earle CC, Lapointe-Shaw L, Krzyzanowska MK, Louie AV, Mahar A, Urbach DR, McIsaac DI, Enepekides D, Gomez D, Look Hong NJ, Tinmouth J, Eskander A. Cancer Med. 2023; 12(10):11849-59. Epub 2023 Mar 31.

Journal Article

27/03/2023

Association of preoperative medical consultation with reduction in adverse postoperative outcomes and use of processes of care among residents of Ontario, Canada

Beckerleg W, Kobewka D, Wijeysundera DN, Sood MM, McIsaac DI. JAMA Intern Med. 2023; 183(5):470-8. Epub 2023 Mar 23.

Journal Article

10/03/2023

Polysomnographic assessment of sleep disturbances in cancer development: a historical multicenter clinical cohort study

Kendzerska T, Murray BJ, Gershon AS, Povitz M, McIsaac DI, Bryson GL, Talarico R, Hilton J, Malhotra A, Leung RS, Boulos MI. Chest. 2023; 164(2):517-30. Epub 2023 Mar 10.

Journal Article

22/02/2023

Association between familiarity of the surgeon-anesthesiologist dyad and postoperative patient outcomes for complex gastrointestinal cancer surgery

Hallet J, Sutradhar R, Jerath A, d’Empaire PP, Carrier F, Turgeon A, McIsaac DI, Idestrup C, Lorello G, Flexman A, Kidane B, Kaliwal Y, Chan WC, Barabash V, Coburn N, Eskander A. JAMA Surg. 2023; 158(5):465-73. Epub 2023 Feb 22.

Journal Article

24/01/2023

Variation in anesthesiology provider-volume for complex gastrointestinal cancer surgery: a population-based study

Hallet J, Sutradhar R, Eskander A, Carrier FM, McIsaac D, Turgeon AF, d’Empaire PP, Idestrup C, Flexman A, Lorello G, Darling G, Kidane B, Kaliwal Y, Barabash V, Coburn N, Jerath A. Ann Surg. 2023; 278(4):e820-6. Epub 2023 Jan 24.

Journal Article

17/01/2023

Survival and healthcare costs after inpatient elective surgery: comparison of patients with and without chronic obstructive pulmonary disease

Sankar A, Thorpe K, McIsaac DI, Luo J, Wijeysundera DN, Gershon AS. CMAJ. 2023; 195(2):E62-71. Epub 2023 Jan 17.

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News Coverage

News Release

25/11/2020

Spinal or epidural anesthesia associated with increased survival compared to general anesthesia for leg artery bypass surgery

News Release

05/06/2018

Ten days or more in the ICU after cardiac surgery tied to high risk of death and healthcare costs

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Contact Details

Get in touch with
Daniel I McIsaac

Twitter: @mcisaac_d

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Daniel I McIsaac

Biography

Education

Research Focus

Other Affiliations

ICES Grants

STRIVE before surgery trial: a vanguard pragmatic multicenter randomized trial of Structured TRaining to Improve fitness in a Virtual Environment before surgery

PREPARE Trial: a parallel arm multicenter randomized trial of frailty-focused PReoperative Exercise to decrease PostoperAtive complication Rates and disability scorEs

Safe Analgesia For Elders receiving Peripheral Nerve Blocks for hip fracture (SAFE PNB)

Awards & Recognition

Junior Research Chair in Perioperative Health Systems and Outcomes Research

Journal Articles

A quasi-experimental evaluation of the association between implementation of Quality-Based Procedures funding for hip fractures and improvements in processes and outcomes for hip fracture patients in Ontario: an interrupted time series analysis

Association of preoperative anaesthesia consultation prior to elective noncardiac surgery with patient and health system outcomes: a population-based study

Association between opioid prescription profiles and adverse health outcomes in opioid users referred for sleep disorder assessment: a secondary analysis of health administrative data

Association between the COVID-19 pandemic and first cancer treatment modality: a population-based cohort study

Early survival for patients newly diagnosed with cancer during COVID-19 in Ontario, Canada: a population-based cohort study

Association of preoperative medical consultation with reduction in adverse postoperative outcomes and use of processes of care among residents of Ontario, Canada

Polysomnographic assessment of sleep disturbances in cancer development: a historical multicenter clinical cohort study

Association between familiarity of the surgeon-anesthesiologist dyad and postoperative patient outcomes for complex gastrointestinal cancer surgery

Variation in anesthesiology provider-volume for complex gastrointestinal cancer surgery: a population-based study

Survival and healthcare costs after inpatient elective surgery: comparison of patients with and without chronic obstructive pulmonary disease

News Coverage

Spinal or epidural anesthesia associated with increased survival compared to general anesthesia for leg artery bypass surgery

Ten days or more in the ICU after cardiac surgery tied to high risk of death and healthcare costs

Get in touch with
Daniel I McIsaac

Daniel I McIsaac

Biography

Education

Research Focus

Other Affiliations

ICES Grants

STRIVE before surgery trial: a vanguard pragmatic multicenter randomized trial of Structured TRaining to Improve fitness in a Virtual Environment before surgery

PREPARE Trial: a parallel arm multicenter randomized trial of frailty-focused PReoperative Exercise to decrease PostoperAtive complication Rates and disability scorEs

Safe Analgesia For Elders receiving Peripheral Nerve Blocks for hip fracture (SAFE PNB)

Awards & Recognition

Junior Research Chair in Perioperative Health Systems and Outcomes Research

Journal Articles

A quasi-experimental evaluation of the association between implementation of Quality-Based Procedures funding for hip fractures and improvements in processes and outcomes for hip fracture patients in Ontario: an interrupted time series analysis

Association of preoperative anaesthesia consultation prior to elective noncardiac surgery with patient and health system outcomes: a population-based study

Association between opioid prescription profiles and adverse health outcomes in opioid users referred for sleep disorder assessment: a secondary analysis of health administrative data

Association between the COVID-19 pandemic and first cancer treatment modality: a population-based cohort study

Early survival for patients newly diagnosed with cancer during COVID-19 in Ontario, Canada: a population-based cohort study

Association of preoperative medical consultation with reduction in adverse postoperative outcomes and use of processes of care among residents of Ontario, Canada

Polysomnographic assessment of sleep disturbances in cancer development: a historical multicenter clinical cohort study

Association between familiarity of the surgeon-anesthesiologist dyad and postoperative patient outcomes for complex gastrointestinal cancer surgery

Variation in anesthesiology provider-volume for complex gastrointestinal cancer surgery: a population-based study

Survival and healthcare costs after inpatient elective surgery: comparison of patients with and without chronic obstructive pulmonary disease

News Coverage

Spinal or epidural anesthesia associated with increased survival compared to general anesthesia for leg artery bypass surgery

Ten days or more in the ICU after cardiac surgery tied to high risk of death and healthcare costs

Get in touch with Daniel I McIsaac

Get in touch with
Daniel I McIsaac